C. R. Bard, Inc.

Clearstream Technologies Limited

Becton Dickinson and Company Limited

Ethicon, Gmbh

Codman & Shurtleff, Inc.

Hiep Do

Darren R Sherman

Yufu Li

Gene W Kammerer

Dhanuraj S Shetty

Sridevi N Dhanaraj

Chunlin Yang

Iksoo Chun

Michael Adam Randall

Sanyog Manohar Pendharkar

Anne Jessica Gorman

Simmi Kalirai

Jerry Moore

Jeffrey Chun Wang

Majid Mehrpouyan

Marybeth Sharkey

Jordan Addison

Andrew Schaffer

Michael A Randall

Oleg Guryev

Paul Fillmore

Jeffrey Wang

Cyal Lecy

Faith C Chamas

Emily Goel

Matthew Gounis

Elena Afonina

Kelly R Arnold

Richard Champion Davis Iii

Sridevi Dhanaraj

Paul (deceased) Fillmore

Methods for preparing a drug-loaded microbead compositions and embolization compositions include loading a therapeutic agent into a water-swellable polymer material to form microbeads, then removing water from the microbeads. The drug-loaded microbead compositions include microbeads of a water-swellable polymer material and a complex of a carrier and a therapeutic agent chemically bonded to the carrier. The complex is embedded in the polymer material. The therapeutic agent is not chemically bonded to the water-swellable polymer material. The drug-loaded microbead composition has a water content of less than 1% by weight, based on the total weight of the drug-loaded microbead composition. The drug-loaded microbead composition may be rehydrated to form an embolization composition for use in in embolization therapy.

Drug-loaded microbead compositions, embolization compositions and associated methods

A hemostatic biopsy tract article includes a bioresorbable body having a microporous structure. The bioresorbable body is formed by a mixture that includes a bioabsorbable hemostatic powder, a hydrolyzed starch, hyaluronic acid, and carboxymethylcellulose. Optionally, a marker element may be coupled to the bioresorbable body, wherein the marker element is formed from a material that is imageable under at least one imaging modality.

Hemostatic biopsy tract article

An interventional medical device, and method of manufacturing the same, is provided to reduce risk to the patient of a fracture of the interventional medical device. At least one portion of the interventional medical device that is subject to fracture and migration within a patient is identified. A membrane is applied over each portion of the interventional medical device that is subject to fracture and migration, such that any fractured portion of the interventional medical device is tied together by the membrane.

Interventional medical device having reduced fracture risk

Drug-loaded microbead compositions include microbeads of a water-swellable polymer material and a complex of a carrier and a therapeutic agent chemically bonded to the carrier. The complex is embedded in the polymer material. The therapeutic agent is not chemically bonded to the water-swellable polymer material. The drug-loaded microbead composition has a water content of less than 1% by weight, based on the total weight of the drug-loaded microbead composition. The drug-loaded microbead composition may be rehydrated to form an embolization composition for use in in embolization therapy. Methods for preparing the drug-loaded microbead compositions and the embolization compositions include loading a therapeutic agent into a water-swellable polymer material to form microbeads, then removing water from the microbeads.

Drug-loaded microbead compositions include microbeads of a biodegradable material and vesicular agents located within or associated with the biodegradable material of the microbeads. The vesicular agents include a lipid bilayer and comprise liposomes or ethosomes. The drug-loaded microbeads include a first therapeutic agent associated with the vesicular agents, and a second therapeutic agent different from the first therapeutic agent. The vesicular agents include a lipid bilayer surrounding a vesicular core. The second therapeutic agent is contained within the microbeads or associated with the microbeads through ionic or non-covalent interaction and may or may not be associated with the vesicular agents. Drug-loaded biodegradable microbead compositions include microbeads of biodegradable material and a therapeutic agent.

Drug-loaded biodegradable microbead compositions including drug-containing vesicular agents

A method and apparatus are aimed to improve arteriovenous fistula maturation rate by treating the fistula with a crosslink agent solution (fixative solution). The fixative solution will crosslink proteins and biomolecules, allowing formation of crosslinks that stabilize or stable tissue structure. The method and apparatus will address factors that contribute to arteriovenous fistula maturation failure by stopping the neointimal hyperplasia growth after vascular injury and stabilizing the venous wall to prevent the lumen from narrowing.

Method and apparatus for enhancing the maturation rate of an arteriovenous fistula

A medical balloon is provided for which the working surface may be identified during an interventional procedure with enhanced precision. Related methods of manufacturing such a balloon are also disclosed.

Apparatuses and methods for providing radiopaque medical balloons

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Chandler, AZ, United States of America

Hiep Do