Seiren Kabushiki Kaisha

Seiren Company, Ltd

Other

Hideyuki Yamada

Kazuhisa Tsujimoto

Hiroshi Takagi

Shigeru Nakamori

Masahiro Sasaki

Yoichi Kato

Masakazu Takahashi

Masakazu Nomura

Satoshi Terada

Katsue Osada

Keiko Yamasaki

Hidekazu Shiomi

Kohei Yamada

Akimitsu Bamba

Keiji Nozaki

Taizo Hamada

Norihisa Kato

Akihiro Nogata

Kouichi Kugimiya

Koichi Okano

Sadayuki Yuda

Kazunobu Tokunaga

Naozumi Fuwa

The purpose of the present invention is to provide a method for using a metal ion solution of low concentration to efficiently form a metal film pattern of excellent accuracy and reliable adhesion on a resin substrate. A resin substrate having a metal film pattern formed thereon is produced by a method that includes the following steps (a) to (e): (a) a step for pattern-printing of a latent image agent () onto the surface of a resin substrate () ; (b) a step for bringing the area imprinted with the latent image agent () into contact with a solution containing metal ions, and forming a metal salt (); (c) a step for bringing the metal salt () into contact with an acidic treatment liquid containing a reducing agent, and reducing the metal salt; (d) a step for forming an electroless nickel plating film () on the area imprinted with the latent image agent; and (e) a step for precipitating an electroless copper plating () onto the surface of the nickel plating film ().

Method for producing a resin substrate having a metal film pattern formed thereon

A composition for the cryopreservation of cells according to the present invention at least comprises sericin and one or more components selected from the group consisting of amino acids and saccharides. Further, a method for the cryopreservation of cells according to the present invention comprises the steps of placing target cells in the abovementioned composition for the cryopreservation of cells and cryopreserving them. According to the composition for the cryopreservation of cells of the present invention, cells can be cryopreserved over a long period of time without the use of serum and components derived from serum.

Compositions for cryopreservation of cells

The present invention relates to an adiponectin production enhancer comprising sericin as an active ingredient, and to a pharmaceutical composition and food and drink comprising sericin. These are effective in the prevention and/or amelioration of various diseases caused by reduction of blood adiponectin level such as arteriosclerosis, fatty liver and diabetes associated with obesity. The enhancer, the pharmaceutical composition and the food and drink according to the invention have excellent adiponectin production enhancing effects as well as high safety and are expected to be broadly applied to a variety of pharmaceutical preparations and food and drink.

Adiponectin production enhancer

The purpose is to prevent, ameliorate or relieve various conditions induced in the dried oral cavity or to improve the stability of a denture during use. A solution for treating a denture or a denture stabilizer comprising sericin can be used.

Use of sericin for improving the feeling in use of denture

This invention provides a transparent electrically conductive film, which, while maintaining the light transparency of a transparent film, has excellent electrical conductivity, can be utilized for electromagnetic wave shielding, and does not cause inclusion of air bubbles in the lamination onto other base material, and a process for producing the same. The production process comprises the steps of forming a large number of concaves and convexes having an average height of not more than 0.1 &#x3bc;m on both sides or one side of a transparent film, forming a resist layer having a pattern shape opposite to the electrically conductive part in the electrically conductive film on the transparent film on its concave-convex side, applying a catalyst for plating onto the resist layer-formed face, separating the resist layer, forming a metal layer by plating, and blackening the metal layer, the metal layer satisfying 1&#x2266;W/T&#x2266;500 wherein W represents the width of the metal layer and T represents the height of the metal layer.

Transparent electrically conductive film and process for producing the same

An object of the present invention is to provide a medium supplement for animal cell culture and an animal cell culture medium. The present invention relates to a medium supplement for animal cell culture comprising sericin or a sericin derivative and an animal cell culture medium comprising at least said medium supplement and a basal medium composition.

Medium supplement and animal cell culture medium

The present invention provides a porous body high in safety against environment and living bodies and having a strength high enough to withstand practical use, said porous body comprising, as a skeleton constituent thereof, sericin with an average molecular weight of 30000 to 400000, and having a recovery rate of 10 to 100% after 50% compression.

Porous body formed of sericin

A peptide according to the present invention is selected from the group consisting of: (a) a peptide having the amino acid sequence represented by SEQ ID NO: 1; (b) a peptide having a modified amino acid sequence of the amino acid sequence described in (a) above, in which one or more amino acid residues are deleted, substituted, inserted or added, and having cell death-preventing activity and/or cell growth-promoting activity; and (c) a peptide which has an amino acid sequence having at least 80% homology with the peptide consisting of the amino acid sequence described in (a) above and has cell death-preventing activity and/or cell growth-promoting activity. The peptide has cell death-preventing activity and/or cell growth-promoting activity, is highly safe, and can be produced without difficulty. The peptide is useful as a culture supplement or as an effective component for a cell culture medium.

Physiologically active peptides

An objective of the present invention is to provide a new protein derived from the silkworm middle silk gland and a DNA encoding said protein. The present invention relates to a protein of the following (a) or (b): (a) a protein comprising the amino acid sequence represented by SEQ ID NO: 1; (b) a protein comprising a modified amino acid sequence of the amino acid sequence described in (a) above, in which one or more amino acid residues are deleted, substituted, inserted or added, and having protease activity.

Protein and DNA encoding the same

Medium additives and media for culturing animal cells

An objective of the present invention is to provide a means to prevent freeze-induced decrease in protein activity. The present invention relates to a method for preventing freeze-induced decrease in protein activity comprising adding a polypeptide comprising the following amino acid sequence (I) to a protein to be frozen. Further, the present invention relates to use of a polypeptide comprising the following amino acid sequence (I) to produce an agent for preventing freeze-induced decrease in protein activity: 

Method of preventing decrease in the activity of protein due to freezing and use of polypeptide in the production of protein activity decrease preventing agent

An object of the present invention is to provide a cosmetic for nail that suppresses dryness of nails, that makes nails hard to fracture, that makes nails glossy as they are, that keeps or improves healthiness of nails, and that is highly safe. The cosmetic for nail is provided by adding 0.02 to 20% by weight of sericin as an effective ingredient additionally to the conventional cosmetic ingredients.

Nail cosmetics

This invention relates to a composition useful as an antioxidant or an inhibitor for tyrosinase activity which comprises as an active ingredient a sufficient amount of sericin to exert an antioxidizing ability or an inhibiting action on tyrosinase activity and this composition is applicable as an antioxidant or a tyrosinase activity inhibitor in the field of medicines, quasi-drugs, medicines for external use, cosmetics, foods, food additives or the like.

Use of sericin as antioxidants and tyrosinase inhibitors

Functional fiber products are provided. The functional fiber products are those adhered thereto a protein containing 20% to 40% by weight of serine as an amino acid component and those adhered thereto sericin and deacetylated chitin.

Growing community of inventors

Fukui, Japan

Hideyuki Yamada