Osaka University

Hideya Kawaji

Kohji Nishida

Motokazu Tsujikawa

Susumu Hara

Satoshi Kawasaki

Masahito Yoshihara

Masayoshi Itoh

Hiroko Ohmiya

Provided is a means for identifying cells suitable for transplantation into a cornea, or a means for producing a cell population suitable for transplantation into a cornea using the same. A method for producing a cell population suitable for transplantation into a cornea, the method comprising the steps of (1) preparing a cell population cultured under conditions suitable for inducing differentiation into corneal endothelial cells, and (2) measuring the expression of at least one gene selected from the group consisting of POU6F2, LMX1B, and TFAP2B in the cell population.

Corneal endothelial cell marker and use thereof

A molecular marker expressed specifically in corneal endothelial cells, and a method for producing one or more corneal endothelial cells using the marker and a method for evaluating one or more corneal endothelial cells using the marker are provided. At least one molecule selected from the group consisting of ZP4, MRGPRX3, GRIP1, GLP1R, HTR1D, and CLRN1 is used as a marker specific to corneal endothelial cells.

Corneal endothelial cell marker

Growing community of inventors

Saitama, Japan

Hideya Kawaji