Shimadzu Corporation

Hidetoshi Terada

Hiroshi Ohashi

Tadayuki Yamaguchi

Yuzi Kanazawa

Shinji Kanazawa

Hiroyuki Yasuda

Yuji Katsuyama

Yusuke Hida

Yohei Yamada

Takeshi Osoekawa

Akihiro Kunisawa

Yusuke Osaka

Katsuhiko Miwa

Chie Kushibe

A pH management system of a liquid chromatograph includes a pH meter that measures a pH value of a mobile phase in the liquid chromatograph, and a warner that presents a warning in a case where it is determined that a pH value measured in the pH meter is different from a set pH value, or that the pH value measured in the pH meter deviates from the set pH value and an error rate exceeds a predetermined error rate, when the pH value measured in the pH meter and the set pH are compared to each other.

PH management system of liquid chromatograph and computer readable recording medium recording program

A chromatograph apparatus control device according to the present disclosure is a control device for controlling a chromatograph apparatus having the function of a liquid chromatograph and that of a supercritical fluid chromatograph. The control device includes a first-type method file creator configured to create a first-type method file describing a condition of an analysis by a liquid chromatograph; a second-type method file creator configured to create a second-type method file describing a condition of an analysis by a supercritical fluid chromatograph; and a batch file creator configured to create a single batch file including a plurality of records describing a group of method files including the first-type method file and the second-type method file, with one method file in each record.

Control device for chromatograph apparatus

A model constructed by a training process using the technique of deep learning using the training data including images created from a large number of chromatograms and correct peak information is previously stored in a trained model storage section. When chromatogram data for a target sample acquired with an LC measurement unit are inputted, an image creator converts the chromatogram into an image and creates an input image in which one of the two areas divided by the chromatogram curve as the boundary in the image is filled. A peak position estimator inputs the pixel values of the input image into a trained model using a neural network, and obtains the position information of the starting point and/or ending point of the peak and a peak detection confidence as the output. A peak determiner determines the starting point and/or ending point of each peak based on the peak detection confidence.

Waveform analyzer

The present invention aims at reducing the time required for a series of analyses in the sequential performance of gradient analyses under a variety of conditions. To this end, in a control apparatus for controlling the operation of a liquid chromatograph having a gradient analysis function in which a mobile phase composed of a plurality of mixed solvents is used and a chromatograph analysis is performed while the mixture ratio of the solvents is temporally changed, the liquid chromatograph is controlled so as to continuously change the mixture ratio of the solvents from an initial mixture ratio to a final mixture ratio when performing a sample analysis; and as to perform, before the sample analysis, a preparatory liquid supply in which the mixture ratio of the solvents is continuously changed from the initial mixture ratio to the final mixture ratio at a rate higher than that in the sample analysis.

Control system and program for liquid chromatograph

Provided is a preparative separation liquid chromatograph system and preparative separation condition searching method which allows for an easy setting of the preparative separation condition. A sample temporally separated into components by a separation column is introduced into a detector and a fraction collector, with each component fractionated and collected by the fraction collector based on the result of a detection by the detector. A controlling and processing unit holds the following data for each sample or compound in the form of a database: chromatogram data obtained when a liquid chromatograph analysis in a preparative separation condition searching mode is performed for various standard samples under a search condition; and chromatogram data obtained when a liquid chromatograph analysis in a preparative separation mode is performed under one or more sets of preparative separation conditions for the various standard samples, along with the preparative separation condition used in this analysis.

Preparative separation liquid chromatograph system and preparative separation condition searching method

A liquid chromatograph control system for controlling an operation of a liquid chromatograph which uses a mobile phase composed of a mixture of solvents and which has the function of performing a gradient analysis while temporally changing the mixture ratio of the solvents. The system initially requests a user to set a basic gradient profile (Step S), and subsequently, to set the number of steps to change the mixture ratio of the mobile phase at the beginning and/or at the end of the gradient process as well as the amount of change in the mixture ratio per step (Step S). After that, based on the possible combinations of the mixture ratios of the mobile phase at the beginning and at the end of the gradient process computed from the contents of information entered in the previous steps, a plurality of gradient profiles corresponding to those combinations are created (Step S).

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Kyoto, Japan

Hidetoshi Terada