Snow Brand Milk Products Co., Ltd.

Show Brand Products Co., Ltd.

Hidetoshi Ishikawa

Atsushi Serizawa

Yukihiro Takada

Seiichiro Aoe

Tomoe Yoshioka

Yasuharu Itagaki

Seiji Kurosawa

A highly safe bone resorption suppressing agents, which can be used as medicines or admixed to food products or feeds, is produced. Milk-derived basic cystatins and/or milk-derived basic cystatin decomposition products prepared from milk are made into bone resorption suppressing agents, or admixed to drinks, food products and feeds.

Bone resorption suppressing agent

A whitening cosmetic preparation containing angiogenin as an effective component is disclosed. Angiogenin used in the present invention may be derived from milk, especially bovine milk. The whitening cosmetic preparation contains at least 0.001% by weight, preferably from 0.01 to 20% by weight angiogenin based on the total amount of said preparation. A method for whitening skin comprising administration of angiogenin to skin is also disclosed. The whitening cosmetic preparation inhibits melanin production and prevents the developments of blotches and freckles of skin.

Whitening cosmetic preparation and method of using same

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Sapporo, Japan

Hidetoshi Ishikawa