Japan Tobacco Inc.

Hideto Uehara

Koji Ando

Koji Matsuda

Shuji Miyake

Takashi Matsuda

Takahisa Motomura

Motohide Satoh

Kentaro Kondo

Provision of a stabilized crystal of 6-(3-chloro-2-fluorobenzyl)-1-[(S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (compound A). A crystal of compound A, which shows a particular X-ray powder diffraction pattern of a characteristic diffraction peaks at diffraction angles 2&#x3b8;(&#xb0;) as measured by X-ray powder diffractometry.

Stable crystal of 4-oxoquinoline compound

Provision of a stabilized crystal of 6-(3-chloro-2-fluorobenzyl)-1-[(S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-1, 4-dihydroquinoline-3-carboxylic acid (compound A). A crystal of compound A, which shows a particular X-ray powder diffraction pattern of a characteristic diffraction peaks at diffraction angles 2&#x3b8;(&#xb0;) as measured by X-ray powder diffractmetry.

Growing community of inventors

Osaka, Japan

Hideto Uehara