Nippon Soda Co., Ltd.

Hideo Takagi

Kazuhiko Ohkuma

Hiroaki Nakamura

Akiyoshi Ueda

Izumi Kumita

Yoshiji Sugita

Akira Nakata

Shogo Kosaka

Compounds of the general formula ##STR1## wherein Xn is 2-Cl, 3-Cl, 2,3-Cl.sub.2 or 3-CF.sub.3, and

Phenylpyrol derivatives

A novel protein adsorbent having a group of the general formula ##STR1## wherein X is hydrogen, halogen, amino, lower alkyl or lower alkoxycarbonyl as a ligand, is useful for the purification of urokinase by hydrophobic chromatography, particularly for the removal of the kinds of pyrogen that can only be removed with great difficulty by affinity chromatography on the ordinal adsorbent of urokinase.

Protein adsorbent and process for the purification of urokinase

Compounds of the general formula ##STR1## wherein X is halogen, lower alkyl or lower haloalkyl, and

Cyanopyrrole derivatives

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Kanagawa, Japan

Hideo Takagi