Kurita Water Industries Ltd.

Hideo Sugi

Ayako Sekikawa

Kenji Tahara

Ryoichi Takahashi

Fumio Toda

Isao Joukou

An antimicrobial composition comprises a clathrate compound containing a water-soluble microbicide, and a dispersion medium. For example, the composition may comprise of a clathrate compound containing a water-soluble microbicide and having a particle size of 200 mesh at maximum, said clathrate compound being formed of 5-chloro-2-methyl-4-isothiazoline-3-one and at least one polymolecular host compound selected from the group consisting of 1, 1-di (2,4-dimethylphenyl)-2-propyne-1-ol; 1,1,6,6-tetra(2,4-dimethylphenyl)-2,4-hexadiyne-1,6-diol; 1,1-bis(4-hydroxyphenyl)cyclohexane; N,N,N',N'-tetra(cyclohexyl)-[1,1'biphenyl]-2,2'-dicarboxyamide; 2,2'-methylenebis(4-chlorophenol), deoxycholic acid; and 2,5-di-tert-butylhydroquinone and a dispersion medium.

Antimicrobial dispersion composition

A clathrate compound which comprises diethyltoluamide and a polymolecular host compound capable of taking up diethyltoluamide. The host compound is bisphenol compounds. Diethyltoluamide is stabilized by forming the clathrate compound.

Clathrate compound and process for stabilizing diethyltoluamide

A clathrate compound comprising a water-soluble microbicide and at least one of (a) a bisphenol compound represented by formula (I) and (b) deoxycholic acid represented by formula (II):

Clathrate compound

A clathrate compound is produced if a powdery host compound which reacts with a microbicide to form the clathrate compound is added into an aqueous solution of the microbicide. If the microbicide is separated from the clathrate compound, a microbicide of high purity can be obtained.

Method of producing a clathrate compound

Method of purifying a microbicide

A clathrate compound comprises a natural essential oil or synthetic perfume, and deoxycholic acid. Deoxycholic acid or a solution containing deoxycholic acid is mixed with a natural essential oil or synthetic perfume to produce the clathrate compound.

A sustained release aromatic comprises a clathrate compound composed of a perfume and a polyphenyl compound and gives out fragrance slowly but steadily over a long period of time. It is produced by a process comprising melting under heat a perfume which is a solid at an ordinary room temperature, and adding a polyphenyl compound to the molten perfume. Alternatively, a perfume which is a liquid at an ordinary room temperature is mixed with a polyphenyl compound so that they may react with each other, and a solid reaction product is separated from their mixture.

Sustained release aromatic

Diphenic acid bis(dicyclohexylamide) represented by the following formula: ##STR1## A process for producing diphenic acid bis(dicyclohexylamide) represented by the above formula, which comprises dimerizing a diazonium salt of o-aminobenzoic acid in the presence of a reducing agent, followed by acidification to give 2,6'-dicarboxylbiphenyl; converting this dicarboxylic acid to 2,6'-dichloroformylbiphenyl by chlorination; and reacting this acid chloride with dicyclohexylamine. Sustained release antimicrobial compositions comprising a clathrate compound consisting of a microbial agent and diphenic acid bis(dicyclohexylamide) represented by the above formula.

Diphenic acid bis(dicyclohexylamide) for clothrate compound, process for

A sustained release antimicrobial agent comprises a clathrate compound composed of a water-soluble microbicide and at least one of the compounds shown at (I) to (V) below:

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Tokyo, Japan

Hideo Sugi