Meito Sangyo Kabushiki Kaisha

Hideo Nagae

Kyoji Kito

Masakatsu Hasegawa

Akihiro Mizutani

Yoshio Ito

Shusaburo Hokukoku

Nahoko Tozawa

Kimio Hirose

Keiko Yamada

Yasuji Yamashita

Masahiro Ohgai

Hisato Yamada

Wolfgang Ebert

Akira Misaki

Mayk Kresse

Susanne Wagner

Shigeo Maruno

Takao Ogawa

Detlef Pfefferer

Rudiger Lawaczeck

Yukari Hino

Taketoshi Komori

Hideki Miyaji

Hiromi Hanai

Hideki Miyachi

Takamasa Hanaichi

Mariko Kakuta

Katsutoshi Murase

Mineo Nakayama

Polysaccharide derivative/magnetic metal oxide composite

Water-soluble carboxypolysaccharide-magnetic iron oxide complex having a

Oxidized complex comprising water-soluble carboxypolysaccharide and

Composition comprising magnetic metal oxide ultrafine particles and

.beta.-1,3-glucanpolyol derived from .beta.-1,3-glucan produced by a .beta.-1,3-glucan-producing strain of the genus Pestalotia, said glucanpolyol having an intrinsic viscosity [.eta.] of about 1 to about 10 and comprising a main chain having as repeating units .beta.-1,3-glucopyranose units of the following formula

.beta.-1,3-Glucanpolyol, process for preparation thereof, and

A pharmaceutical composition containing as its active ingredient a disaccharide derivative having a derivative group of the following formula (1) bonded to a carbon atom of a disaccharide: ##STR1## wherein Y is a member of the group consisting of NH and O; and when Y is NH, Z is a member of the class consisting of --O-- (disaccharide residue) and --O--, with the proviso that one of the two bonds is attached to the other carbon atom of the same disaccharide to which the formula (1) group is bonded, and when Y is O, Z is a member of the class consisting of --NH.sub.2 and --O--, with the proviso that one of the two bonds is attached to a carbon atom of a disaccharide different from that to which the formula (1) group is bonded. The disaccharide derivative can be prepared by reacting a disaccharide with an activating agent selected from the group consisting of the cyanogen halides, organic cyanic acid esters and halogenocarbonic acid alkyl esters. Said pharmaceutical composition is useful for treating hepatic diseases.

Disaccharide derivatives used in the treatment of hepatic diseases

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Kasugai, Japan

Hideo Nagae