Kumamoto University

Sbi Pharmaceuticals Co., Ltd.

University of Occupational and Enviromental Health, Japan

National University Corporation Kumamoto University

Hidenori Itoh

Tohru Tanaka

Tetsuya Yoneda

Shigeru Nishizawa

Junkoh Yamamoto

[Problem] To provide a nuclear magnetic resonance diagnostic agent that has a lower toxicity to organisms and reduced side effects and yet has a site specificity toward a specific cell, tissue, organ, etc. [Solution] When ALA or an ALA derivative is administered in vivo, a metabolite thereof is accumulated in a specific cell, tissue, organ, etc. Focusing on this phenomenon, a nuclear magnetic resonance analysis was performed on a site wherein the metabolite of ALA that had been administered in vivo would be possibly accumulated. As a result, it was surprisingly found that ALA and an ALA derivative are useful as a diagnostic agent whereby the aforesaid problem can be solved.

Nuclear magnetic resonance diagnostic agent, and method for detecting or diagnosing state of cell, tissue or organ in subject using same

Growing community of inventors

Tokyo, Japan

Hidenori Itoh