Takeda Pharmaceutical Company Limited

Hideki Saitoh

Mitsuhisa Yamano

Toshiaki Nagata

The present invention relates to a graft copolymer of a poly(amino acid) or a salt thereof and a hydrophobic primary amine compound or a salt thereof (e.g., a graft copolymer (&#x3b3;-PGA-PAE) of poly(&#x3b3;-glutamic acid) (&#x3b3;-PGA) and phenylalanine ethyl ester (PAE)), an ionized graft copolymer of a poly(amino acid) or a salt thereof and a hydrophobic primary amine compound or a salt thereof, nanoparticles containing the ionized graft copolymer, and a production method thereof. The nanoparticles acquired in this way are useful as an adjuvant for producing a vaccine.

Growing community of inventors

Osaka, Japan

Hideki Saitoh