Seikagaku Kogyo Kabushiki Kaisha

Japan Science and Technology Agency

Japan Science and Technology Corporation

Hidekazu Oyamada

Shu Kobayashi

Jinichi Inokuchi

Masayuki Jinbo

Takeshi Naito

Ryo Akiyama

The present invention provides a polysilane-supported transition metal catalysts or a polysilane/inorganic compound-supported transition metal catalysts, wherein various types of transition metals are supported by polysilane compounds, or combination of polysilanes and inorganic compounds. The catalysts of the present invention are hardly soluble in hydrocarbons and alcohols and are useful as catalysts in heterogeneous system for various organic synthetic reactions using the above solvents. Polysilanes supporting transition metals are easily crosslinkable by thermal treatment, microwave irradiation, UV irradiation or chemical methods such as hydrosilylation reaction and are changed to be insoluble in various solvents keeping high catalytic activity. Moreover, the stability and operability of polysilane-supported transition metal catalysts will be improved by the support thereof on inorganic compounds. These polysilane-supported transition metal catalysts show a high catalytic activity in hydrogenation reaction, hydrosilylation reaction, Heck reaction, Suzuki-Miyaura coupling reactions and the like. The catalyst is easily recoverable and reusable and the leakage of metals is extremely few.

Polysilane-supported transition metal catalyst for liquid phase reaction

Amino alcohol derivative and method for preparing the same

Hydrazide fixed to a resin and derivatives thereof, and a method for synthesizing pyrazolones in solid phase

Amino alcohol derivatives with a primary amino group or a substituted amino group influence the synthesis of glycolipids and have antiviral, antitumor, metastasis inhibiting and neural cell growth enhancing functions. The amino alcohol derivatives are useful in preparing 2-acylamino alcohol derivatives.

Growing community of inventors

Saitama, Japan

Hidekazu Oyamada