Toray Industries, Inc.

Hidekazu Nakashima

Shigehisa Wada

Hidetoshi Kozawa

Hiroyuki Sugaya

Hiroshi Matsumoto

Tsutomu Uesaka

Katsuyoshi Ichikawa

Madoka Kawashima

A dialyzer for blood treatment including a semipermeable membrane which is made of a hydrophobic polymer and a hydrophilic polymer, and has a water permeating performance drying of &#xbd; or higher relative to that before drying. The dialyzer has a vitamin B12 clearance not smaller than 135 ml/mm per 1.6 mor the amount of the hydrophilic polymer eluted from the semipermeable membrane is not higher than 10 ppm. A dialyzer for blood treatment is light-weight, easy to handle, and exhibits a reduced elution of the hydrophilic polymer procedures for producing a dialyzer containing the semipermeable membrane and a process for producing a hollow fiber membrane for use in blood treatment are described.

Dialyzers for blood treatment and processes for production thereof

A dialyzer for blood treatment includes a semipermeable membrane which is made of a hydrophobic polymer and a hydrophilic polymer, and has a water permeating performance drying of &frac12; or higher relative to that before drying. The dialyzer has a vitamin B12 clearance not smaller than 135 ml/min per 1.6 m or the amount of the hydrophilic polymer eluted from the semipermeable membrane is not higher than 10 ppm. A dialyzer for blood treatment is light-weight, easy to handle, and exhibits a reduced elution of the hydrophilic polymer procedures for producing a dialyzer containing the semipermeable membrane and a process for producing a hollow fiber membrane for use in blood treatment as described.

A blood processing apparatus which retains little residual blood is provided by a hollow fiber flux fixed to a housing by a partition, with the end portion opened. A blood port provided with a blood intake is attached to the opened end plane. The angle of the blood intake interior wall of the blood port has an inclination &thgr; of 1.5&deg; or less as to the center axis of the blood port. The distance h of the interior face of the blood port and the flux-holding partition it faces is 0.08 D&lE;h&lE;0.13 D where Q represents the intersection between a hypothetical line which passes through the end portion P of the inner plane of the blood port and is orthogonal with the partition and a hypothetical extension line from the ceiling plane of the blood port, h represents the distance between the partition and the intersection Q, and D represents the diameter at the end portion of the inner plane of the blood port. The blood processing apparatus is used for blood purifying, dialysis, ultrafiltration, and the like.

Growing community of inventors

Shiga, Japan

Hidekazu Nakashima