Colin Corporation

Fukuda Denshi Co., Ltd.

Hidekatsu Inukai

Akihiro Yokozeki

Toshihiko Ogura

Keizoh Kawaguchi

Tohru Oka

Hiroshi Sakai

Hiroshi Sakai, Deceased

Takashi Nomura

Tomoko Ikawa

Toru Oka

Kiyoyuki Narimatsu

Tomohiro Nunome

Yoshihisa Miwa

Masayuki Shinoda

Hiroshi Masuda

A blood pressure monitoring apparatus which continuously estimates and monitors the blood pressure by using the pulse wave propagation time can accurately estimate the blood pressure. While an estimated blood pressure is continuously calculated by using the pulse wave propagation time, the correlation between the pulse wave propagation time and the interval between feature points contained in two consecutive heart beat waveforms of an electrocardiogram is monitored. If the correlation is reversed, the blood pressure is actually measured, and the estimated blood pressure is corrected on the basis of the difference between the estimated blood pressure and actually measured blood pressure.

Blood pressure monitoring apparatus

In blood pressure monitoring apparatus which continuously estimates and monitors blood pressure by using the pulse wave propagation time, blood pressure fluctuation can be accurately estimated. If both blood pressure estimated from the pulse wave propagation time and a waveform parameter obtained from the accelerated pulse wave have abnormal values, it is determined that the blood pressure is truly fluctuating, and blood pressure measurement by another method, e.g., blood pressure measurement using a cuff is performed.

A pulse wave is detected in a predetermined location of a living body, and the progressive wave component and reflected wave component are extracted from the pulse wave. The pulse wave propagation time is calculated from the progressive wave component and reflected wave component, and blood pressure is calculated on the basis of this pulse wave propagation time. The use of this method provides blood pressure measuring apparatus capable of continuously measuring blood pressure with a simple method.

Blood pressure measuring apparatus

A blood pressure monitor apparatus for monitoring a blood pressure of a living subject, comprising: pulse-wave-propagation-velocity-relating information obtaining means for successively obtaining pulse-wave-propagation-velocity-relating information which relates to a pulse-wave propagation velocity at which a pulse wave propagates in an artery of the subject; pulse-period-relating information obtaining means for successively obtaining pulse-period-relating information which relates to a pulse period of the subject; peripheral-blood-volume-relating information obtaining means for successively obtaining peripheral-blood-volume-relating information which relates to a volume of blood which flows in a peripheral body portion of the subject; and abnormality judging means for judging that the blood pressure of the subject is abnormal when at least one of the pulse-wave-propagation-velocity-relating information, pulse-period-relating information, and peripheral-blood-volume-relating information does not fall within a corresponding one of a first, a second and a third reference range.

Blood pressure monitor apparatus

An apparatus for measuring a propagation velocity of a pulse wave which is propagated through an artery of a living subject, the apparatus including an electrocardiographic-waveform detecting device which detects an electrocardiographic waveform from the subject, a pulse-wave sensor which is adapted to be worn on the subject and which detects the pulse wave from the subject, a time-difference determining device for determining a time difference between a first periodic point relating to the detected electrocardiographic waveform and a second periodic point relating to the detected pulse wave, and a propagation-velocity determining means for determining the propagation velocity of the pulse wave based on the determined time difference.

Apparatus for measuring pulse-wave propagation velocity

An apparatus for estimating a blood pressure of a living subject, including a measuring device which iteratively measures a blood pressure of the subject, a first device for obtaining first information relating to velocity of propagation of pulse wave, a second device for obtaining at least one of second information relating to heart rate and third information relating to area defined by volume pulse wave, a memory which stores groups of information each group of which includes the blood pressure, the first information, and at least one of the second information and the third information, a determining device for determining an expression representing a relationship between (A) blood pressure, and (B ) first information and (B ) at least one of (B ) second information and (B ) third information, and having a first coefficient for the first information, at least one second coefficient for at least one of the second and third information, and a constant, the determining device determining the coefficients and constant of the expression by applying a multiple regression analysis to more than a predetermined number of groups of information last stored in the memory, the predetermined number being equal to a total number of the coefficients and the constant, and an estimating device for successively estimating, according to the expression, a blood pressure of the subject based on each first information and at least one of each second information and each third information.

Blood pressure estimating apparatus

A blood pressure monitor apparatus for monitoring a blood pressure of a living subject, comprising: blood pressure-relating information obtaining means for successively obtaining blood pressure-relating information which decreases or increases with a decrease or an increase of the blood pressure of the subject, or blood pressure-relating information which increases or decreases with a decrease or an increase of the blood pressure of the subject; decrease or increase determining means for determining a decrease or an increase of the blood pressure-relating information successively obtained by the obtaining means; and abnormality judging means for judging that the blood pressure of the subject is abnormal when the decrease or increase of the blood pressure-relating information is greater than a predetermined reference value (&ggr; , &ggr; ), or abnormality judging means for judging that the blood pressure of the subject is abnormal when the blood pressure-relating information is greater than a predetermined reference value (TH ) or smaller than a predetermined reference value (TH ).

A device for monitoring the blood pressure of a living subject, including a pulse-wave-propagation-velocity-relating information obtaining device for successively obtaining pulse-wave-propagation-velocity-relating information which relates to a pulse-wave propagation velocity at which a pulse wave propagates in an artery of the subject, a pulse-period-relating information obtaining device for successively obtaining pulse-period-relating information which relates to a pulse period of the subject, a peripheral-blood-volume-relating information obtaining device for successively obtaining peripheral-blood-volume-relating information which relates to a volume of blood which flows in a peripheral body portion of the subject, and an abnormality judging device for judging that the blood pressure of the subject is abnormal when at least one of the pulse-wave-propagation-velocity-relating information, pulse-period-relating information, and peripheral-blood-volume-relating information does not fall within a corresponding one of a first, a second and a third reference range.

An apparatus for iteratively measuring a blood pressure of a living subject who is undergoing a blood-dialysis treatment, including an inflatable cuff which applies a pressing force to a body portion of the subject, a blood-pressure measuring device which measures a blood pressure of the subject by changing the pressing force of the cuff, a starting device for starting the blood-pressure measuring device at a predetermined period in the dialysis duration, so that the blood-pressure measuring device iteratively measures a blood pressure of the subject at the predetermined period, a period memory device which stores, for a plurality of living subjects including the subject, a plurality of sets of predetermined periods each set of which includes respective predetermined periods for a plurality of partial durations of the dialysis duration, an identifying device for identifying the subject, and a selecting device for selecting, from the sets of predetermined periods stored in the period memory device.

Blood-pressure measuring apparatus for patient under blood-dialysis treatment

A blood-pressure monitor, including a blood-pressure measuring device including a cuff, an information obtaining device which iteratively obtains, from a living subject, physical information which changes with change of blood pressure of the subject, a measurement starting device for starting a measurement of the blood-pressure measuring device, when a subsequent piece of information obtained by the obtaining device after the measuring device has measured a last blood pressure of the subject in a last measurement thereof has been deviated by not less than a predetermined amount from an initial piece of information obtained by the obtaining device when the measuring device measured the last blood pressure of the subject, a display device which displays a graph representing the pieces of information obtained by the obtaining device, and a control device which controls the display device to display the graph representing the initial piece of information and each one of subsequent pieces of information iteratively obtained by the obtaining device after the measuring device has measured the last blood pressure of the subject, so that the initial piece of information and the each one subsequent piece of information can be compared with each other.

Blood-pressure monitor apparatus

An apparatus for estimating an intraarterial blood pressure of a living subject, based on information non-invasively obtained from a circulatory organ of the subject, including: a first device for obtaining first information which relates to velocity of propagation of a pulse wave; a second device for obtaining at least one of second information which relates to heart rate and third information which relates to an area defined by a volume pulse wave; a third device for estimating, according to a predetermined relationship to between (A) blood pressure, and (B1) first information and (B2) at least one of (B21) second information and (B22) third information, the blood pressure, based on the first information and the at least one of the second information and the third information, the predetermined relationship being defined by a numerical expression including a plurality of predetermined coefficients; and a fourth device for selecting, from a plurality of groups of predetermined coefficients which correspond to a plurality of blood-pressure ranges, respectively, one group of predetermined coefficients which corresponds to a blood pressure, so that the third device estimates the blood pressure according to the numerical expression including the selected group of predetermined coefficients.

Blood pressure estimating apparatus and method

An apparatus for successively estimating an intraarterial blood pressure of a living subject, based on information non-invasively obtained from a circulatory organ of the subject, including: a first device for non-invasively obtaining, from the circulatory organ of the subject, first information which relates to velocity of propagation of a pulse wave which propagates through an artery of the subject; a second device for non-invasively obtaining, from the circulatory organ of the subject, at least one of second information which relates to heart rate of the subject and third information which relates to an area defined by a volume pulse wave from a peripheral portion of the subject; and a third device for estimating, according to a predetermined relationship between (A) blood pressure, and (B1) first information and (B2) at least one of (B21) second information and (B22) third information, the intraarterial blood pressure of the subject, based on the first information obtained by the first device and the at least one of the second information and the third information obtained by the second device.

An apparatus for estimating an intraarterial blood pressure of a living subject, based on information of the subject, including: a first device for obtaining first information which relates to velocity of propagation of a pulse wave; a second device for obtaining at least one of second information which relates to heart rate and third information which relates to an area defined by a volume pulse wave; a third device for estimating, according to a predetermined relationship between (A) blood pressure, and (B1) first information and (B2) at least one of (B21) second information and (B22) third information, the blood pressure of the subject, based on the first information and the at least one of the second and the third information, the relationship being defined by a numerical expression including a plurality of coefficients; a fourth device for determining an activity of an autonomic nerve system, based on at least one of fourth information which relates to fluctuations of the blood pressure and fifth information which relates to fluctuations of the heart rate; and a fifth device for changing, based on the activity of the autonomic nerve system, at least one of the coefficients of the expression, so that the expression including the changed coefficient amplifies a change of an estimated blood pressure from a prior estimated blood pressure.

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Nagoya, Japan

Hidekatsu Inukai