Universal Bio Research Co., Ltd.

Precision System Science Co., Ltd.

Other

Pss Bio Instruments, Inc.

The Furukawa Electric Co., Ltd.

Precision Systems Science Co., Ltd.

Furukawa Electric Advanced Engineering Co., Ltd.

Roche Diagnostics Gmbh

Iatron Laboratories Inc.

454 Life Sciences Corporation

Percision System Science Co., Ltd.

Fi-techno Co., Ltd.

Bio Strand, Inc.

University Bio Research Co., Ltd.

Hideji Tajima

Tetsuya Ueda

Ken Tsukii

Masahisa Noguchi

Takaki Sugimoto

Osamu Segawa

Yoshinao Hirahara

Yoshiro Okami

Masaki Mamiya

Yu Sugiyama

Yukiko Miyashita

Shuichi Kobayashi

Yu Matsukubo

Tomoyuki Hatano

Shuuichi Kobayashi

Ryouji Karinaga

Kazuhiro Nakamura

Hiroshi Suzuki

Mitsunao Tanaka

Minoru Ogasawara

Hermann Leying

Nathan Kane

Susumu Kimura

Masanari Tsujimura

Masataka Fumoto

Yoshinori Koh

Nobuo Nagaoka

Tomomi Saegusa

Michinori Koizuka

Tsutomu Asano

Junko Asahina

Mamiko Yoshida

Donald I Stimpson

Kimimichi Obata

Claus Bamberg

Volker Degenhardt

Madoka Shishido

Mitsuo Itakura

An optical measurement device is provided. The device includes first and second optical fibers; first and second reaction vessels, and a light guide stage coupled to the first and second optical fibers. The light guide stage is driven to simultaneously optically connect the first and second optical fibers with the first and second reaction vessels. The device includes a measurement device for receiving emissions from the first and second reaction vessels, and a connecting end arranging body that supports the first and second optical fibers along a path. The arranging body is driven along the path between a first position, in which the first optical fiber is optically connected with the measurement device so that light is transmittable from the first reaction vessel, and a second position, in which the second optical fiber is optically connected with the measurement device so that light is transmittable from the second reaction vessel.

Optical measurement device for reaction vessel and method therefor

A photometric dispensing nozzle unit, a photometric dispensing apparatus, and a photometric dispensing method are for preventing an increase in apparatus scale and have a simple structure to be easily handled. A nozzle performs suction/discharge of gas through a distal end opening and can have a dispensing tip attached thereto. A light guide end portion is provided in the nozzle and can receive or irradiate light at a distal end of the nozzle. A dispensing cylinder has a cylinder having a cavity therein, a plunger that is slidable in the cavity, and a suction/discharge port that performs suction/discharge of gas. A suction/discharge flow path passes through the nozzle and communicates with the suction/discharge port and the distal end opening of the nozzle. A light guide path is optically connected to the light guide end portion through the nozzle but not through the dispensing cylinder.

Photometric dispensing nozzle unit, photometric dispensing apparatus, and photometric dispensing method

A dispensing cylinder capable of performing a dispensing treatment for both minute and large amounts of liquid includes: a cylinder having a cavity; a nozzle provided at one end of the cylinder, having a through hole in fluid communication with the cavity and extending in an axial direction of the cavity, and a plunger slidable in the cavity in the axial direction. The cavity has a large diameter region having a large inner peripheral surface and a small diameter region having a second inner peripheral surface. The plunger has a thick shaft portion slidable in the large diameter region and a thin shaft portion protruding from a distal end of the thick shaft portion in the axial direction and slidable in the small diameter region.

Dispensing cylinder, and dispensing device and dispensing treatment method using same

A cartridgefor nucleic acid detection is provided with: a first memberhaving multiple nucleic acid extraction wells; a second memberhaving a nucleic acid amplification and determination well for amplification of a nucleic acid and detection of the amplified nucleic acid; and multiple reagent containers. The multiple reagent containersare fixed between the first memberand the second member

Cartridge for nucleic acid detection

This culture device comprises: a culture container which houses cells, magnetic particles and a culture medium; a temperature adjustment unit for adjusting the temperature of the culture container; a magnet which is provided to the outside of the culture container; a magnetic force adjustment unit for adjusting the magnetic force of the magnet; and a control unit for controlling the operation of the magnetic force adjustment unit. The magnetic force adjustment unit adjusts the magnetic force of the magnet, thereby holding magnetic particles and cells in a predetermined region within the culture container, or dispersing the magnetic particles and cells within the culture container.

Culture device, culture system, and culture method

The specimen treatment and measurement systemaccording to the present invention is provided with: a movement stagehaving a plurality of treatment lanes for treating specimens in parallel; a consumables supply modulefor storing consumables for use in treatment of the specimens, and supplying the consumables to the movement stage; a cartridge supply modulefor storing cartridges for use in treatment of the specimens, and supplying the cartridges to the movement stage; and a stage transfer mechanismfor transferring the movement stageto each module. The cartridge supply modulehas a plurality of cartridge cartons for accommodating the cartridges stacked on top of each other, and a push-out mechanism for pushing cartridges out of a cartridge carton to a supply position of the cartridge supply module

Specimen treatment and measurement system

A specimen treating and measuring system according to the present invention comprises: a treatment part having a plurality of lanes for carrying out parallel processing of a plurality of specimens, and mounting cartridges in each of the plurality of lanes; a cartridge storing unit storing a plurality of types of cartridge to be used for different processes corresponding to the plurality of specimens; a sample storing unit storing and conveying sample tubes containing the plurality of specimens; a pickup unit transferring each of the plurality of types of cartridge to each lane, and transferring each of the plurality of specimens from the sample tubes to each of the plurality of lanes; and a control unit controlling the transfer of the plurality of types of cartridge and the transfer of the plurality of specimens, performed by the pickup unit.

Specimen processing and measuring system

The invention relates to an optical measurement device for a reaction vessel, and a method therefor. An object is to measure the optical state within a reaction vessel in an efficient, rapid, and highly reliable manner, without an expansion of the device scale. The configuration includes: a vessel group in which two or more reaction vessels are arranged; a light guide stage having two or more linking portions to which front ends of light guide portions, which have a flexibility, that optically connect with the interior of the linked reaction vessels, are provided; a connecting end arranging body that has an arranging surface that arranges and supports along a predetermined path two or more connecting ends, to which back ends of the light guide portions, in which the front ends thereof are provided to the linking portions, are provided, the connecting ends are provided corresponding to the respective linking portions; a measurement device provided approaching or making contact with the arranging surface that has measuring ends that are successively optically connectable with the respective connecting ends along the predetermined path, and in which light from within the reaction vessels is receivable by means of optical connections between the connecting ends and the measuring ends; and a light guide switching mechanism that relatively moves the respective connecting ends arranged on the connecting end arranging body and the respective measuring ends such that they are successively optically connected.

A highly-reliable absorbance measuring device that enables highly-accurate measurement of absorbance, and a method thereof are provided. A liquid containing unit that can contain a chemical substance solution to be measured, a nozzle that communicates with a suction/discharge mechanism that sucks/discharges gas, a flow tube that includes a mouth part, which can be inserted into the liquid containing unit, at a lower end and that is detachably attached to the nozzle at an upper end, an emitting end that can emit measurement light, a light receiving end that can receive the light emitted from the emitting end, and a control unit are included. The control unit is configured to suck a prescribed amount of the chemical substance solution into the flow tube, and to lead absorbance on the basis of intensity of transmitted light acquired by emission of measurement light in a vertical direction into the flow tube.

Absorbance measuring device and method thereof

A general-purpose optical measuring device enables at least measurement of a nucleic acid amplification amount; detection or quantitative measurement by a nucleic acid detection method, an immunoassay method, an enzyme method; or measurement of concentration or absorbance, and a method of the same. There are included a photometric content designation unit, an irradiation reception pair including an emission end that can emit measurement light, and a reception end that can receive light from the emission end, a photometric container that can store measurement target chemical substance solution, and includes a bottom portion having a formed translucent region, a nozzle communicated with a suction discharge mechanism of gas, a flow tube, an optical measurement unit, and a control unit configured to suck and hold the chemical substance solution into the flow tube, or store the chemical substance solution into the photometric container.

General-purpose optical measuring device and method of same

It is an object to provide a deforming element-included dispensing tip, a deforming element-included dispensing device, and a deforming element-included dispensing processing method not requiring any cylinder and capable of achieving highly precise position control and enhancing integration of higher density and reducing the burden in the quality control in reaction processing of a biological material for extraction of DNA and the like. A tip-shaped container formed with a non-deforming wall having an opening portion at an upper side and an inlet unit at a lower side for allowing fluid to flow in and flow out and a sealing plug attached to the opening portion so as to seal the opening portion are provided, and the sealing plug is configured to be provided with a deforming element.

Deforming element-included dispensing tip, deforming element-included dispensing device, and deforming element-included dispensing processing method

In a method of nucleic acid extraction using a support, the present invention realizes collection of a nucleic acid from a liquid containing the nucleic acid at an extremely low concentration at which collection cannot be achieved with polyacrylamide. A method of extracting a nucleic acid, comprising allowing the nucleic acid to be adsorbed onto a support in the presence of a chaotropic salt and an alcohol in coexistence with an anionic polymer. A reagent for nucleic acid extraction, comprising an anionic polymer, a chaotropic salt, an alcohol and a support.

Method and reagent for extracting nucleic acid

A multiple reaction parallel measurement apparatus is intended to measure a large number of reactions quickly, simply and with high accuracy. The apparatus includes: a plurality of light guiding paths corresponding to a plurality of reaction spot array elements, including a measuring end able to be in proximity of or in contact with each one of the reaction spots, and arranged to guide light generated by a reaction at the reaction spot to a connecting end; a measurement head arranged such that the measuring ends reach all together predetermined measurement positions of the corresponding reaction spots of the reaction spot array elements at a predetermined scan period; a light guiding path selector including a light guiding region optically connected to the connecting end; a light receiving unit; and a digital data converter to obtain digital data by converting image region data obtained from the light receiving unit.

Multiple reaction parallel measurement apparatus and method for the same

A reaction container control system including a reaction container, a sealing lid, a temperature control block, and a heater. The reaction container includes a lower side wall section, an upper side wall section, and an aperture. The sealing lid seals the reaction container by fitting to the aperture of the reaction container. When the sealing lid is fitted to the aperture, light based on an optical state within the reaction container is receivable by a measuring device via the sealing lid. The temperature control block contacts or extends adjacent the lower side wall section, and includes a temperature source operable to increase or decrease a temperature inside the reaction container. The heater contacts or extends adjacent the upper side wall section, and includes a heat source operable to heat the reaction container to prevent condensation on the sealing lid fitted to the aperture.

Reaction container control system

An apparatus and related method to reliably prevent cross-contamination and to decrease working time or space involved with reaction treatment. The apparatus includes: a container group having one or more reaction containers and two or more liquid storage portions arranged in a linear shape; a dispensing head to which one or more dispensing tips insertable into the container group are detachably attached, the dispensing head being relatively movable with respect to the container group in a linear direction; a magnetic portion provided in the dispensing head and capable of: applying a magnetic field into each dispensing tip so that the magnetic particles are adsorbed to an inner wall of the dispensing tip, and removing the magnetic field so that the magnetic particles are resuspended in a solution; and an ultrasonic vibration device which applies ultrasonic vibration to a sample storage portion including at least one of the liquid storage portions.

Linear movement type reaction treatment apparatus and method thereof

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Matsudo, Japan

Hideji Tajima