Yakurigaku Chuo Kenkyusho

Nisshin Flour Milling Co., Ltd.

Hidehiko Takahashi

Yoshikuni Suzuki

Koji Maeda

Katsumi Imada

Yumiko Tomiya

Susumu Hara

Akira Motoshio

A process for the preparation of ceramide by using erythrocytes as a starting material is disclosed herein. For the purpose of obtaining ceramide at a low cost and in a large amount, ceramide is prepared by means of hydrolysis or enzymolysis of sphingolipid existing in sphingomyelin. According to the preparation process of the present invention, ceramide useful as a moisturizer for human skin can be obtained at a low cost and in a large amount by relying upon erythrocytes as a starting material.

Process for preparing sphingomyelin and ceramide from erythrocyte as a

A composition having lipase inhibiting activity is prepared by extracting defatted rice germ with water at room temperature. That composition, which is useful in preventing or treating obesity, can be incorporated into food products.

Lipase inhibitor derived from a defatted rice germ

Disclosed is a novel process for the production of pyrocomenic acid [3-hydroxy-4(1H)-pyran-4-one and rubiginol [3,5-dihydroxy-4(1H)-pyran-4-one, which are starting materials for synthesis of maltols useful as food spices as well as additives for cosmetics. The chemical reactions possibly taking place in the fermentation and the heating post-treatment thereof in the present invention are shown as follows: ##STR1## The microorganisms usable in the above oxidation fermentation include Gluconobacter rubiginosus IFO 3244, Gluconobacter suboxydans IFO 3254, Gluconobacter melanogenus IFO 3293, Pseudomonas fluorescens IFO 3081, Erwinia carotovara IFO 3380 etc.

Process for preparation of gamma-pyrone derivatives

A dieting agent is disclosed which comprises an aqueous solution or a solid substance of a concentration .alpha.-amylase inhibiting substance which is produced by a process which comprises heat treating a supernatant fraction of an aqueous extract of wheat or wheat flour to modify unnecessary protein contaminants in the supernatant fraction, removing a modified protein from said fraction, subjecting a resulting aqueous solution containing an .alpha.-amylase inhibiting substance to a concentration treatment using an ultrafiltration membrane to form an aqueous solution of a concentrated .alpha.-amylase inhibiting substance or drying the aqueous solution. The dieting agent exhibits a body weight gain-inhibiting effect.

Dieting agents comprising .alpha.-amylase inhibiting substances

Disclosed is use of a synthetic aluminum silicate as antacid and anti-ulcer preparation, anti-obesity preparation and acne curing preparation. This aluminum silicate is obtained by reacting an aluminum compound and silicic acid or water glass at a weight ratio Al.sub.2 O.sub.3 : SiO.sub.2 of 4.5:1.0-6.0:1.0 in a strongly acidic aqueous solution having an initial pH of 1.0-3.0, then adding thereto a basic substance to reach excess in alkali and then neutralizing the reaction mixture to pH 5.0-7.0 with an acid.

Novel synthetic aluminum silicate preparation

An absorbent prepared by supporting an organic or inorganic reductive substance on hydrated aluminum silicate is useful as a pharmaceutical or as an absorbent for precious metal complexes such as gold complex, silver complex and the like.

Hydrated aluminum silicate adsorbent supporting reductive substance

Novel acyl compounds 3-acyloxy-4(H)-pyran-4-ones were obtained by reacting 3-hydroxy-4(H)-pyran-4-one with acyl halides. The acyl compounds and their starting compound exhibit a skin-lightening effect on the skin and are preferably used as an active constituent in skin-lightening cosmetic preparations or local demelanizing agents.

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Tokyo, Japan

Hidehiko Takahashi