Medrx Co., Ltd

Nippon Shinyaku Company, Ltd.

Teikoku Seiyaku Co., Ltd.

Rohto Pharmaceutical Co., Ltd.

Aspion Co., Ltd.

Hideakira Yokoyama

Hidetoshi Hamamoto

Takeru Fujii

Keiko Yamasaki

Akihiko Hirata

There is provided an external preparation for wounds which has novel usability in treating skin damages accompanied by a large amount of exudation such as bedsores, skin ulcers, and burns, and yet has such advantages as observed in conventional medicines having been employed in treating these wounds. The external preparation for wounds comprises a water-soluble polymer and a crosslinking agent, and has powdery/granular or ointment form. After absorbing an exudation, the preparation undergoes phase transition from a sol to a gel by the action of ingredient of the preparation, and thus exhibits actions of adsorbing and eliminating necrotic tissues, and protecting the wounded parts. Subsequently, it can continuously absorb the exudation. After being used, it can be easily separated substantially as a mass, thereby exhibiting high therapeutic effects and usability.

External preparation for wounds

The peptide in this invention is a peptide having affinity to gp120 represented by Formula (1): H-A1-A2-A3-A4-A5-R(SEQ ID No. 1) The above peptide has an affinity to gp120 of the HIV envelope protein and is superior in stability.

Peptide having an affinity for gp120

This invention relates to external drugs for dermal application which have a migraine-alleviating effect, in more detail ointments and patches comprising in mixing l-menthol and an essential oil into a base containing a hydrophilic high-molecular weight compound, a polyhydric alcohol and water.

Drugs for relieving hemicrania comprising 1-menthol and essential oils

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Tokushima, Japan

Hideakira Yokoyama