Reverse Proteomics Research Institute Co., Ltd.

Hideaki Sueoka

Morikazu Kito

Yorimasa Suwa

Takeshi Tsutsumi

Tadakazu Yamauchi

Yuko Isono

Kouichi Tsuchiya

Kazuo Komiya

Katsuhisa Murayama

Ken Horiuchi

Motoi Tobita

The present invention provides novel target proteins and target genes for drug discovery, and the means that enable the development of novel drugs using the same. More particularly, the present invention provides NCS proteins and genes thereof; screening methods for drug (for example, anti-central nervous disease drug); agents for regulating disease (for example, central nervous disease); production methods of a drug derivative; a complex comprising a drug and NCS protein, and a method of producing the complex; a kits comprising a drug or a salt thereof; determination methods for the onset or risk of onset of a specified disease, determination methods for susceptibility to a drug, and determination kits used for the determination methods; and the like.

Drug development target protein and target gene, and method of screening

The present invention provides a novel target protein and a gene for drug discovery, and a means that enables development of a novel pharmaceutical agent by using the same. More particularly, the present invention provides CARP and genes thereof; screening methods for drugs (e.g., antiallergic drugs); a regulator of diseases (e.g., allergic diseases); a drug derivative production method; a complex comprising a drug and CARP, and a production method thereof; kits comprising a drug or a salt thereof; determination methods for the onset or risk of onset of a specified disease, determination methods for susceptibility to a drug, and determination kits used for said methods, and the like.

Target protein and target gene in drug designing and screening method

Growing community of inventors

Osaka, Japan

Hideaki Sueoka