Chugai Seiyaku Kabushiki Kaisha

Hideaki Nagai

Noriko Kawamura

Yasushi Murakami

Masuo Koizumi

Masamitsu Honda

Takashi Dan

Yoshikazu Hinohara

Shoko Takishima

Hideki Nakano

Yoshio Takagaki

Akinori Kawamura

Benzamide derivatives of the formula: ##STR1## wherein R.sub.1 is a hydrogen atom, a methyl group or a methoxy group; R.sub.2 is a straight-chain or branched-chain alkyl group having 2 to 8 carbon atoms, a substituted phenyl group, or group --NHR.sub.4, R.sub.4 being a hydrogen atom, a straight-chain or branched-chain or cyclic alkyl group having 1 to 6 carbon atoms, or a phenyl group that may have a substituent on the nucleus; R.sub.3 is a hydrogen atom or one or two alkyl groups having 1 to 4 carbon atoms and n is 0 or 1, a process for preparing these derivatives, and pharmaceutical compositions containing the same are provided. The compounds of the above formula have the action to reduce the blood glucose level and, therefore, are useful as medicines.

3-Substituted-ureido-N-pyridyl benzamides

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Saitama, Japan

Hideaki Nagai