Tokyo University of Agriculture and Technology

Hirosaki University

Chuo Precision Industrial Co., Ltd.

Bio-giken, Inc.

Canon Kabushiki Kaisha

Hideaki Matsuoka

Nobuhiro Nakamura

Yohei Yamada

Katsuya Yamada

Tadashi Teshima

Toshihiro Yamamoto

Atsushi Fujii

Mikako Saito

Ki-Bong Oh

Yohei c/o Chuo Precision Industrial Co Yamada

An object of the present invention is to provide a method for accurately evaluating the specific incorporation of D-glucose into cells. The present invention as a means for achieving the object is characterized by comprising contacting a D-glucose derivative that has a fluorescent chromophore in the molecule and is specifically incorporated into cells and an L-glucose derivative that has a fluorescent chromophore in the molecule with different cells in the same cell strain to be evaluated, respectively, comparing the fluorescence emitted by the D-glucose derivative that has a fluorescent chromophore in the molecule and is specifically incorporated into cells with the fluorescence emitted by the L-glucose derivative that has a fluorescent chromophore in the molecule, and evaluating the specific incorporation of D-glucose into cells relative to L-glucose by taking the difference between the two kinds of fluorescence intensities.

Method for evaluating specific incorporation of D-glucose into cells

To provide an inexpensive cell incubator for a single cell operation supporting robot having the markers (first and second feature points) required to transform the position of a cell detected on a table coordinate system into a position on the intrinsic coordinate system of the cell incubator. First and second feature points are formed on a film-like feature point setup chip which is then stuck to the cell incubator body such as a conventional dish, thus constituting a cell incubator. Since manufacture of a new die for forming the first and second feature points directly on the cell incubator body is not required, an inexpensive cell incubator for a single cell operation supporting robot can be provided.

Cell incubator for single cell operation supporting robot

A method for regulating the morphological transition of dimorphic Candida in a patient is described. The method comprises administering orally or by injection a compound to a patient suffering from an infection caused by dimorphic Candida selected from the group consisting of,, and,. The compounds are used to regulate the morphological transition of the dimorphic Candida, wherein the compound is selected from the group consisting of:

Compound to regulate the morphological transition of dimorphic candida

A fluorescent imaging method of the changes in viability of living bodies wherein the living bodies are provided with a chemical or physical exterior stimulation and information on the changes in viability of cells caused by the stimulation is obtained by means of a fluorescent imaging method of the saccharide uptake activity by contacting or administering to the living bodies an aqueous solution of a fluorescent saccharide compound which includes at its specific position a saccharide molecule chemically combined with a fluorescent pigment molecule.

Fluorescent imaging method of saccharide uptake activity of living tissue

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Tokyo, Japan

Hideaki Matsuoka