Mitsubishi Kasei Corporation

Research Development Corporation of Japan

Mitsubishi Chemical Corporation

Mitsubishi Chemical Industries Limited

Tohoku Electric Power Company, Inc.

Research Development Corporation

Mitsubushi Kasei Corporation

Hideaki Kiniwa

Akihiro Shimura

Hiroshi Kusano

Masahiko Annaka

Hirohisa Kubota

Yoshimichi Kobayashi

Masao Tomoi

Shintaro Sawada

Tsunehiko Kurata

Teruo Onozuka

Yukio Tsuge

Susumu Hirako

Manabu Shindo

Takashi Nishikaji

A method for demineralizing water or an aqueous solution, which comprises contacting the water or the aqueous solution to be treated to a strongly basic anion exchanger made of a crosslinked polymer having a constituting unit of the following formula (I): ##STR1## wherein A is a C.sub.1-2 linear alkylene group, B is a C.sub.4-8 linear alkylene group, each of R1, R2 and R3 which may be the same or different, is a C.sub.1-4 alkyl group or a C.sub.2-4 alkanol group, X is a counter ion coordinated on the ammonium group, and the benzene ring D may have an alkyl group or a halogen atom as a substituent.

Method for treating water or an aqueous solution

This invention relates to cell culture carriers consisting of a porous support, at least a part of which surface being coated with a water-insoluble polymer constituted by (meth)acrylic acid ester and/or (meth)acrylamides and a cross-linking agent, and having a positively chargeable chemical moiety on the polymer surface. The present carriers have enabled the high-density cell culture in any type of the culture methods.

Cell culture carriers

An adsorbent for optical resolution obtained by graft polymerizing an optically active vinyl monomer of the formula: ##STR1## wherein X is --CONH--, --COO-- or --NHCOO--, R.sup.1 is a hydrogen atom or a methyl group, and each of R.sup.2 to R.sup.4 which are different from one another, is a hydrogen atom, a hydrocarbon group or an alkoxycarbonyl group, or R.sup.2 and R.sup.3 together form a ring, to a crosslinked polymer carrier having groups to which said monomer is graft polymerizable.

Adsorbent for optical resolution and resolution method employing it

A process for producing crosslinked polymer particles which comprises a first step of polymerizing a polymerizable monomer containing from 0.1 to 2.0% by weight, based on the entire polymerizable monomer, of a crosslinkable monomer in a medium in which the polymerizable monomer is soluble but the resulting polymer is insoluble, to obtain crosslinked polymer particles having a particle size of from 0.8 to 10 .mu.m, and a second step of letting the crosslinked polymer particles absorb from 1 to 50 times by weight of a polymerizable monomer containing from 2 to 100% by weight, based on the entire polymerizable monomer, of a crosslinkable monomer in an aqueous medium, followed by polymerization to obtain crosslinked polymer particles having a particle size of from 1 to 30 .mu.m and a crosslinking degree of from 1.0 to 98%.

Process for producing crosslinked polymer particles

A process for producing crosslinked polymer particles which comprises a first step of polymerizing a polymerizable monomer containing from 0.1 to 2.0% by weight, based on the entire polymerizable monomer, of a crosslinkable monomer in a medium in which the polymerizable monomer is soluble but the resulting polymer is insoluble, to obtain crosslinked polymer particles having a particle size of from 0.8 to 10 .mu.m, and a second step of letting the crosslinked polymer particles absorb from 1 to 50 times by weight of a polymerizable monomer containing from 2 to 100% by weight, based on the entire polymerizable monomer, of a crosslinkable monomer in an aqueous medium, followed by polymerization to obtain crosslinked polymer particles having a particle size of from 1 to 30 .mu.m and a crosslinking degree of from 1.0 to 98%

A separation medium useful as an adsorbent of liquid chromatography for optical resolution of racemic mixtures is disclosed, which comprises a reversed phase support coated with an optically active amino acid derivative represented by formula (I): ##STR1## wherein R.sub.1 represents a straight or branched alkyl group having from 1 to 3 carbon atoms; and R.sub.2 and R.sub.3 each represents a straight or branched alkyl group having from 4 to 12 carbon atoms which may contain an aromatic group or an unsaturated alkyl group. The separation medium is applicable to optical resolution of a wide range of DL-amino acids and exhibits excellent durability.

Separation medium

A method of adsorbing a substance such as an optically active substance, comprising contacting a solution of the substance in a solvent with an adsorbent consisting of a cross-linked polymer comprising

Adsorbent and method of preparation

A method of adsorbing a substance such as an optically active substance, comprising contacting a solution of the substance in a solvent with an adsorbent consisting of a cross-linked polymer comprising an optically active, synthetic poly(amino acid) represent by the general formula (I): ##STR1## wherein R stands for an organic group, R' stands for hydrogen or an alkyl group an n is an integer of at least 5, which may be protected at a terminal amino group and a carrier polymer supporting said synthetic poly(amino acid) thereon, said carrier polymer having affinity for said solvent. A method for producing the cross-linked polymer is also described. The adsorbent is especially useful for optical resolution of racemic mixtures.

Method of adsorbing subtances

A method of adsorbing a substance such as an optically active substance, comprising contacting a solution of the substance in a solvent with an adsorbent consisting of a cross-linked polymer comprising an optically active, synthetic poly(amino acid) represent by the general formula (I): ##STR1## wherein R stands for an organic group, R' stands for hydrogen or an alkyl group and n is an integer of at least 5, which may be protected at a terminal amino group and a carrier polymer supporting said synthetic poly(amino acid) thereon, said carrier polymer having affinity for said solvent. A method for producing the cross-linked polymer is also described. The adsorbent is especially useful for optical resolution of racemic mixtures.

Adsorbent

In a cationic electrodeposition process for coating an electric conductive substrate as a cathode with an electrodeposition process-coating composition containing a resin; an improvement characterized in that said resin is a resin having hydroxyl groups, tertiary amino groups, quaternary ammonium groups and blocked isocyanate groups which are reactive with hydroxyl group at an elevated temperature which is obtained by reacting

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Yokohama, Japan

Hideaki Kiniwa