Talis Biomedical Corporation

Hédia Maamar

Thomas Henry Cauley, Iii

John Dixon

Michael John McAdams

David Alexander Rolfe

David Glade

Sayeed Andeshmand

Dzam-Si Jesse Ng

Xuewen Jiang

Nadya Andini

Kathy Chiu

Andrea Dedent

Matt Lee

Shuyuan Ma

Matthew B Lee

Jason M Casolari

Methods and systems are provided for point-of-care nucleic acid amplification and detection. One embodiment of the point-of-care molecular diagnostic system includes a cartridge and an instrument. The cartridge can accept a biological sample, such as a urine or blood sample. The cartridge, which can comprise one or more of a loading module, lysis module, purification module and amplification module, is inserted into the instrument which acts upon the cartridge to facilitate various sample processing steps that occur in order to perform a molecular diagnostic test.

Diagnostic system

Disclosed herein are primers and probes related to the detection of SARS-CoV-2 via nucleic acid amplification testing (NAAT), for example to amplify and determine the presence of SARS-CoV-2 in test samples and/or to diagnose Covid-19. Specifically, the present disclosure describes primers and probes that bind to the N gene, ORF1ab, or E gene of SARS-CoV-2 coronavirus for detection via loop mediated isothermal amplification (LAMP) and molecular beacon hybridization.

Polynucleotides for amplification and detection of SARS-CoV-2

Disclosed herein are primers and probes related to the detection of beta actin [(human)] via nucleic acid amplification testing (NAAT), for example to amplify and determine the presence of β-actin present in test samples. Specifically, the present disclosure describes primers and probes that bind to the beta actin gene for detection via loop mediated isothermal amplification (LAMP) and molecular beacon hybridization.

Polynucleotides for amplification and detection of human beta actin

The invention provides methods and compositions for the detection ofin a test sample. Its presence or absence in the sample is determined by nucleic acid based testing methods using primers and/or probes and or molecular beacons that bind to the 23S ribosomal genes or gene transcripts.

Polynucleotides for the amplification and detection of

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El Dorado Hills, CA, United States of America

Hédia Maamar