Université Joseph Fourier - Grenoble 1

Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale

Centre Hospitalier Universitaire Grenoble

Université Grenoble Alpes

Université Joseph Fourier

Inserm (institut National De La Sante Et De La Recherche Medicale)

Hervé Pelloux

Yung-Sing Wong

Corinne Mercier

Marie-France Delauw

Hélène Fricker-Hidalgo

Mohamed-Ali Hakimi

Alexandre Bougdour

Danièle Maubon

The present disclosure relates to a method for identifying the presence or absence of anti-antibodies in a human or animal serum, including placing the previously drawn serum in contact with antigens capable of binding with the anti-antibodies, and the observation of a bond or of an absence of a bond of antibodies with the antigens, and a combination of two recombinant GRA2 and GRA6 proteins. In particular, the antigens are attached to a support, in particular an ELISA plate. This test is preferably carried out as a supplement to another test for diagnosing toxoplasmosis.

Recombinant GRA antigens and the use of same for early diagnosis of toxoplasmosis

The present invention relates to a method for preparing a cyclic peptide with antiparasite activity and anticancer activity. The invention also relates to this peptide as an antiparasite agent, for example in the treatment of toxoplasmosis and as an anticancer agent. The invention also relates to the use of this cyclic peptide for treating organs ex vivo before transplantation.

Cyclic peptides with an anti-parasitic activity

Growing community of inventors

Bernin, France

Hervé Pelloux