Maat Pharma

Institut National De La Recherche Agronomique

Institut National De Recherche Pour L'agriculture, L'alimentation Et L'environnement

Biocodex

Institut National De Recherche Pour L'agriculture

Hervé Affagard

Carole Schwintner

Joël Dore

Catherine Juste

Fernanda Fonseca

Jean-François Dubuisson

Patricia Lepage

Sylvie Rabot

Amandine Bardy

Alice Leroux

Christel Maillet

Marianne Robin

Cyrielle Gasc

Olivier David

Emilie Plantamura

Benoît Levast

Lilia Boucinha

Corentin Le Camus

Hervé Blottiere

Clémence Mader

Cédric Michenet

Audrey Chapron

The invention relates to the use of fecal microbiota transplant for preventing and/or reducing systemic and gut treatment-induced inflammation in an individual in need thereof.

Fecal microbiota composition for use in reducing treatment-induced inflammation

A sampling method using a sampling device () comprising a container () comprising a body () consisting of a soft pouch, and a lid (), in which at least one among the container () and the lid () is provided with a discharging member () suitable for, in an open state, discharging at least one part of the gases contained in the internal space () of the body () of the container (), wherein the sampling method comprises the steps consisting in: —collecting a biological material in the body () of the container (), and assembling the lid () on the neck (IO) of the container (), —and placing an internal space () of the body () of the container () under anaerobic conditions by placing the discharging member () in the open state, by compressing the body () of the container () and by placing the discharging member () in a closed state.

Microorganism sampling method, microorganism sampling device and sampling kit comprising such a sampling device

The present invention relates to a method for preparing a homogeneous mixture of fecal microbiota from at least two preselected donors. The homogeneous mixture of fecal microbiota thus obtained has a bacterial diversity and an increased viability. The homogeneous mixture of fecal microbiota may be used for treating intestinal dysbiosis and for treating pathologies associated with such dysbiosis.

Stool collection method and sample preparation method for transplanting fecal microbiota

The present invention relates to a pharmaceutical oral formulation for use in the administration of at least two bacteria derived from fecal microbiota to mammals for the treatment and/or prevention of dysbiosis and associated pathologies. The pharmaceutical oral formulation is encapsulated mixture of at least two bacteria derived from fecal microbiota wherein the capsules are coated in a pH responsive polymer composition comprising:

Pharmaceutical oral formulation comprising bacteria

A sampling method using a sampling device () comprising a container () comprising a body () consisting of a soft pouch, and a lid (), in which at least one among the container () and the lid () is provided with a discharging member () suitable for, in an open state, discharging at least one part of the gases contained in the internal space () of the body () of the container (), wherein the sampling method comprises the steps consisting in: &#x2014;collecting a biological material in the body () of the container (), and assembling the lid () on the neck () of the container (), &#x2014;and placing an internal space () of the body () of the container () under anaerobic conditions by placing the discharging member () in the open state, by compressing the body () of the container () and by placing the discharging member () in a closed state.

The present invention relates to a method for preparing a fecal 5 microbiota sample of a donor subject. Said method includes the following steps: a) collecting at least one fecal microbiota sample from the donor subject; b) within a period of less than 5 minutes after collecting the sample, placing said sample obtained in step a) in an oxygen-tight collection device; c) mixing the sample obtained in step b) with at least one aqueous saline 10 solution containing at least one cryoprotectant and/or a filling agent; d) optionally, filtering the mixture obtained in step c), in particular by means of a filter comprising pores having a diameter of less than or equal to 0.7 mm, preferably less than or equal to 0.5 mm; and e) storing the mixture obtained in step c) or d) by freezing said mixture at a temperature 15 of between &#x2212;15&#xb0; C. and &#x2212;100&#xb0; C. Steps b) to e) are carried out in anaerobiosis.

Method of preparing a faecal microbiota sample

Method for lyophilisation of a simple of fecal microbiota. The present invention relates to a method for lyophilisation of a sample of fecal microbiota from a donor subject, comprising the following steps: A) mixing of a sample of fecal microbiota from a donor subject with a diluent selected from polyols, disaccharides to pentasaccharides, maltodextrins and mixtures thereof, and B) freezing the mixture obtained in A) at a temperature of less than &#x2212;50&#xb0; C., preferably of between &#x2212;70&#xb0; C. and &#x2212;100&#xb0; C., followed by the lyophilisation thereof.

Method of lyophilization of a sample of faecal microbiota

Growing community of inventors

Lyons, France

Hervé Affagard