The Johns Hopkins University

Hermenegild Arevalo

Natalia A Trayanova

Henry R Halperin

Jason Constantino

Fijoy Vadakkumpadan

Katherine Wu

A method of planning a patient-specific cardiac procedure according to an embodiment of the current invention includes receiving three-dimensional imaging data of a patient's heart, simulating at least one of electrophysiological or electromechanical activity of at least a portion of the patient's heart using the three-dimensional imaging data, and planning the patient-specific cardiac procedure based on the simulating. The cardiac procedure is for providing a preselected alteration of at least one of electrophysiological or electromechanical behavior of the patient's heart.

System and method for planning a patient-specific cardiac procedure

A method of determining a likelihood of an occurrence of a cardiac arrhythmia in a patient includes receiving three-dimensional imaging data of said patient's heart, constructing a whole-heart model for simulating at least one of electrophysiological activity or electromechanical activity of the patient's heart using the three-dimensional imaging data, simulating a response of the patient's heart to each of a plurality of stimulations to a corresponding plurality of different locations within the patient's heart using the whole-heart model, classifying each simulation outcome for each stimulation as one of a normal heart rhythm or a cardiac arrhythmia, calculating a likelihood index based on results of the classifying, and determining the likelihood of the occurrence of the cardiac arrhythmia in the patient based on the likelihood index. Software and data processing systems that implement the above methods are also provided.

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Hermenegild Arevalo