University Of Zürich

Bionx Implants, Oy

Inion Ltd.

Hermann Sailer

Auvo Kaikkonen

Harri Happonen

Franz Weber

Piet E Haers

Pertti T&ouml;rm&auml;l&auml;

Timo Pohjonen

Jan Nieuwenhuis

Pertti Helevirta

Olli Karhi

Timo Waris

Riitta Suuronen

The present invention relates to a pharmaceutical composition containing a mixture of stable folding variants of recombinant bone morphogenic proteins (rBMPs) and its use in therapy, especially in the treatment of orthopaedic and dental patients. Specifically, the present invention relates to a pharmaceutical composition containing a mixture of stable folding variants of at least two rBMPs or their monomers or mutants in a suitable carrier system.

Pharmaceutical compositions comprising bone morphogenetic protein monomers for inhibiting bone formation

Methods of inhibiting or inducing bone formation

A novel polymer composition is provided which includes a base material including a biodegradable polymer or copolymer, and a copolymer additive including one or more monomers imparting a tensile strength to the polymer composition at room temperature that is lower than a tensile strength at room temperature for the base material.

Resorbable polymer compositions

A surgical tissue fixation system is described, including: (1) a bioabsorbable tissue fixation plate having optionally a plurality of through-holes arranged in alternating relation along the plate; (2) bioabsorbable fasteners adapted for insertion into the through-holes to secure the plate to underlying bodily tissue or bone; and (3) an installation instrument which triggers (strikes or shoots) fasteners one after one, in rapid succession, into the through-holes made through the plate and into the underlying bodily tissue or bone, which also optionally includes drillholes.

Surgical system for tissue fixation

Growing community of inventors

Zurich, Switzerland

Hermann Sailer