Avl Ag

Avl Medical Instruments Ag

Other

Hermann J Marsoner

Erich Kleinhappl

Helmut List

Christoph Ritter

Herbert Kroneis

Otto S Wolfbeis

Hellfried Karpf

Alfred Leitner

Fritz Fischer

Falko Skrabal

Karl Harnoncourt

Horst Ruther

Gerald Kirchmayer

Marco J Leiner

Helmut Offenbacher

Werner E Ziegler

Heinz Kontschieder

Taghi Noormofidi

Massoud Ghahramani

Klaus Putz

Ewald Jobstl

Reinhard Loschnigg

Gunther Savora

Winfried Strutz

A feeder unit, which is used for selectively charging an analyzing apparatus with liquid or gaseous sample-, reference- or cleaning media, comprises a sample inlet and a feeder part hinged on the feeder unit at one end. The feeder part contains an intake passage for the cleaning medium to be entered, the sample inlet having a flexible feeder funnel cooperating with a washing element which is attached to the feeder part and can be introduced into the funnel. The feeder part is configured as a cover flap swinging around a fixed pin. The intake passage for the cleaning medium opens into the washing element and is also used for delivering liquid and gaseous reference media. The washing element is located on a support which is elastically attached to the cover flap, and fits into the flexible funnel when the cover flap is closed.

Feeder unit for selectively charging an analyzing apparatus

A device designed for determining one or more medical variables in living organisms, comprises a part to be inserted into the tissue of the organism, which has an exchange channel with openings into the tissue. The device comprising a delivery unit connected with the exchange channel for the delivery of a perfusion fluid and its drainage after partial equilibration with the medical variable or quantity to be measured, i.e., preferably glucose concentration, and comparatively constant endogenous or exogenous marker variables. The device further comprising an analyzing unit for measuring the medical variable and one marker variable, and an evaluation unit for determining the actual concentration of the medical variable with the use of the marker variables. The proposal is put forward that the part to be inserted into the tissue is configured as a flexible plastic cannula, and that this cannula is provided with a puncturing needle on one end, and that the two ends of the cannula are connected to feeder and drainage tubes of the delivery unit both on the pressure and suction side.

Device for determining at least one medical variable

In order to calibrate a measurement apparatus used for determining at least the pH and pCO.sub.2 values in aqueous media, two aqueous base solutions A and B with good storage stability are mixed at a defined ratio immediately prior to calibration, the desired pH and pCO.sub.2 values being provided for calibration of the measuring electrodes of the measurement apparatus only after chemical reaction of the base solutions A and B has taken place.

Method for calibration of a measurement apparatus

In order to simplify the performance of serial measurements by means of a measuring device for determining chemical parameters of an aqueous sample, with at least one symmetrical, ion-sensitive membrane being located between the sample and an electrolytic medium and the sample and the electrolytic medium being in contact with reference electrodes connected to an evaluation unit, a measuring element is provided which can be inserted into a measuring device and which has a sample chamber connected with a reference chamber via a bore. At least one measuring chamber is provided, which is separated from the sample chamber by a symmetrical, ion-sensitive membrane. The reference chamber and all measuring chambers contain electrolytic media into which are dipped the reference electrodes located in the measuring device.

Measuring device for determining chemical parameters of an aqueous sample

An analyzing apparatus for the purpose of analyzing samples of body fluids, comprising a sample feeding device and a measuring channel in which measuring probes are contained. In order to attain good reproducibility and uniform conditions of treatment of the samples the measuring channel is separated by means of a valve from a storage tank communicating with the sample feeding device.

Analyzing apparatus

Due to the size of the devices used for the excitation and measuring of light, conventional sensor elements for optically determining the concentrations of substances contained in gaseous and liquid samples, featuring an indicator layer with one or more indicator substances, are not well suited for use with microanalysis equipment, nor are they easy to mass-produce. These disadvantages are eliminated by integrating on the carrier layer (1) at least one photosensitive element (3) and its electric contact leads in planar arrangement, and by establishing optical contact between the indicator substance (7, 7') of the indicator layer (6) stimulated by the excitation radiation (11), and the photosensitive elements (3).

Sensor element for determination of concentration of substances

In order to produce a small-volume flow measuring cell with good flow characteristics in a sensor device for determining the concentration of a substrate in a sample medium, comprising an enzyme electrode which is covered by a membrane and a reference electrode, both of which are in contact with the measuring cell, the proposal is put forward that the reference electrode be located outside of the membrane cover of the enzyme electrode and that the maximum extension of the flow measuring cell normal to the flow direction of the sample medium essentially be the same as the diameter of the sensitive layer of the enzyme electrode.

Sensor device

In order to reduce the measuring volume in a device for measuring chemical and physical parameters of liquid or gaseous media by means of optical sensor elements whose optodes may be replaced easily, a measuring unit with a sample channel is provided which may be inserted into a supporting frame of the device and which may be connected to ingoing and outgoing sample lines via capillary bores. The measuring unit contains a sensor carrier forming the boundary of the sample channel on one side, which sensor carrier has bores holding the optodes. The indicator film of each individual optode is situated in the plane of the sensor carrier facing the sample channel.

Device for measuring chemical and physical parameters of a liquid or

In order to improve a one-way measuring element, which may be inserted into an analyzer for analyzing gaseous or liquid samples and which comprises a measuring channel with a measuring zone and one or more sensors located therein, the proposal is put forward that the one-way measuring element be provided with a sensor part whose measuring channel has seals on both ends, and with a sample-taking part, and that a coupling element be placed at the inlet end of the measuring channel for direct coupling of the sample-taking part containing the gaseous or liquid sample, and that the measuring channel be filled with a calibrating and storage medium prior to the measuring process, and that the calibrating and storage medium contained in the measuring channel be displaced by the sample flowing in after the sample-taking part has been coupled to the sensor part. The one-way measuring elements obtained in this way are characterized by great simplicity of design and ease of handling.

One-way measuring element

An analyzing apparatus primarily designed for the analysis of body fluids, includes a feeding device, a measuring unit formed by a string of measuring cells linked by a channel, and a waste disposal unit for removal of the samples analyzed. Such an analyzing apparatus may be tailored to suit specific purposes by providing the measuring unit, or at least parts thereof, as modular units, which can directly be coupled to the feeding device and the waste disposal unit via a separate control block.

Due to the size of the devices used for the excitation and measuring of light, conventional sensor elements for optically determining the concentrations of substances contained in gaseous and liquid samples, featuring an indicator layer with one or more indicator substances, are not well suited for use with microanalysis equipment, nor are they easy to mass-produce. These disadvantages are eliminated by using a unitary sensor element having a carrier layer, at least one photosensitive element with electric contact leads in contact with the carrier layer, and an indicator layer containing an indicator substance.

An analyzing apparatus for the purpose of analyzing samples of body fluids, comprising a sample feeding device and a measuring channel in which measuring probes are contained. In order to attain good reproducibility and uniform conditions of treatment of the samples the measuring channel is separated by a valve from a storage tank communicating with the sample feeding device.

A feeding device with a feeder element for liquid or gaseous samples includes an automatic sample exchanger having sample vessels for the liquid or gaseous samples and openings between the sample vessels through which the feeder element is automatically shifted from the feed position for serial samples to an initial position in contact with a feed opening for calibrating or cleansing media.

Feeding device for introducing liquid or gaseous samples

An apparatus for measuring the properties of a sample includes a sensor block with at least one sensor module whose housing contains a measuring chamber in contact with a sensor, the housing of the sensor module M including a mixing chamber for indirect measurement of a sample property, which chamber is placed upstream of the measuring chamber, and is connected with a sample channel and a reagent channel. Due to the modular design of the sensor block, the sample and reagent paths in the sensor block or sensor module may be kept short; along with the compact arrangement of mixing chamber and measuring chamber this permits the required sample and reagent volumes to be kept to a minimum.

Apparatus for measuring the components of a sample

A feeding device for introducing liquid or gaseous media into the analysis path of an analyzing apparatus includes a feeder element which cooperates in an initial position with a feed opening for calibrating or cleansing media and which may by brought into one or more sample feed positions. The feeder element is fastened by means of chain pins to a driven link chain which is guided by a guide pulley, the chain permitting the feeder element to be moved from the initial position and then tilted into a sample feed position upon contact of the feeder element with the guide pulley.

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Graz, Austria

Hermann J Marsoner