Consortium Fur Elektrochemische Industrie Gmbh

Hermann Braunling

Norman Haberle

Rudolf Kaufmann

Wolfgang Deinhammer

Reinhard Muller

A process for the production of substituted furans of the general formula ##STR1## wherein R is a member of the group consisting of alkoxy radicals having from 1-6 C-atoms, a substituted aryloxy radical, an unsubstituted aryloxy radical and an alkyl radical, R.sub.1 is a alkyl or aryl radical with 1-6 C-atoms, preferably methyl, R.sub.2 and/or R.sub.3 is an alkyl radical with 1-6 C-atoms or hydrogen by reacting a .beta.-dicarbonyl compound with an .alpha.-chlorocarbonyl compound in the presence of a compound capable of combining with the hydrochloric acid formed, at temperatures between 30.degree. and 100.degree. C., the reaction being carried out at pH values between 2 and 7, preferably between 3.5 and 6, with the addition of equimolar amounts of an alkaline earth carbonate.

Process for the production of substituted furans

A process for the manufacture of furancarboxylic acid anilides of the general formula ##STR1## in which R.sub.1 represents an aryl group or an alkyl group, R.sub.2 and R.sub.3 each represent an alkyl group or hydrogen, by a ring-closure reaction of a .beta.-ketoester with an .alpha.-haloaldehyde or .alpha.-haloketone, in the presence of a stoichiometric amount of a halide-binding substance to form a furancarboxylic acid ester, and by subsequent anilidation, the reaction being performed in two stages, the ring-closure reaction being carried out in the presence of a mixture of alkaline earth metal carbonates and pyridine in a ratio of from 1000 to 5:1 Val, based on the hydrohalic acid liberated, at temperatures between 50.degree. and 100.degree. C.; and after separation in said second stage, the furancarboxylic ester is reacted while stirring with aniline in up to 20 times molecular excess, in the presence of equimolar amounts based on the furancarboxylic acid, of magnesium dianilide and/or aluminum trianilide in liquid phase or in suspension at temperatures between 20.degree. and 180.degree. C., under normal pressure. The furancarboxylic acid anilides have an outstanding pesticidal action.

Growing community of inventors

Munich, Germany

Hermann Braunling