Medoptix, Inc.

Other

Bio-chek LLC

Optical Coating Laboratory, Inc.

Optical Sensors, Inc.

Linear Corporation

Raytek Gmbh

Vivomedical, Inc.

Sensor Control, Inc.

Herbert L Berman

Jeffrey N Roe

Robert N Blair

Darius Akbar Sadeghi

James W Moyer

Thomas Arnold Peyser

Russell O Potts

James C Sprout

James T Christol

Mikhail A Kouchnir

Michael R Jacobs

Richard W Singer

Described are devices, methods, and kits for non-invasively measuring glucose. In general, the devices comprise skin patches for placement on a skin surface and measurement devices for measuring glucose collected in the patches. The patches may include an adhesive material, a collection layer, an interface layer, and a sweat-permeable membrane. The sweat-permeable membrane is configured to act as a barrier to epidermal contaminants and glucose brought to the skin surface via diffusion. In this way, non-correlatable skin surface glucose will not be measured. The patches may further include components to induce a local sweat response. The measurement device typically includes a display, a processor, and a measurement mechanism. The methods typically include the steps of wiping the skin surface with a wipe containing at least one solvent for removing glucose, placing a patch on a skin surface, and measuring glucose collected in the patch. Kits comprising the patch and measurement device are also described.

Devices, methods, and kits for non-invasive glucose measurement

Highly portable, handheld instrument which can be pointed at the produce to be checked. Light from a source within the instrument is directed onto the produce to induce fluorescent emission from the produce, and fluorescent emissions from the produce are monitored with a detector within the instrument to detect the presence of pesticide residue on the produce. The light from the source is filtered to selectively pass light of a wavelength which induces maximum fluorescent emission from the pesticide to be detected, and the emissions from the produce are filtered to selectively pass emissions having a spectral content characteristic of the pesticide to be detected.

Pesticide detector and method

This involves non-invasive glucose measurement processes for determining blood glucose level in the human body. After achieving a static level of glucose at a surface of the skin over some period of time, the glucose may then be measured by a variety of different processes. A sample of the glucose may also first be extracted from the skin and this sample may then be measured. Clearly, these processes are especially suitable for monitoring glucose levels in the human body, and is especially beneficial to users having diabetes mellitus. These procedures may be used for other analyte materials that are found in appropriate regions of the outer skin.

Glucose measurement utilizing non-invasive assessment methods

A patient monitor system implemented by a service provider for users via recording a patient's analytes measurements by an attenuated total reflection (ATR) infrared total spectroscopy method. The system comprises an input module that provides a non-invasive method in measuring analytes in a patient, such as a measurement of the glucose level and other blood analytes. The measurement is shared among a plurality of output devices such as computers, personal digital assistants (PDAs), cellular phones, and pagers that are stationed or held by various users, such as doctors, patients, researchers, pharmacies, labs, and health insurers. In addition, behavioral attributes are recorded and correlated with the analytes measurements to generate a profile. The profile is selectively sent to output devices based on the user profile corresponding to the output device. Also, access to the profile is monitored by a security module that encrypts the profile to prevent access by un-authorized users.

Method and system of monitoring a patient

This involves a non-invasive glucose measurement device and a process for determining blood glucose level in the human body using the device. In typical operation, the glucose measurement device is self-normalizing in that it does not employ an independent reference sample in its operation. The device uses attenuated total reflection (ATR) infrared spectroscopy. Preferably, the device is used on a fingertip and compares two specific regions of a measured infrared spectrum to determine the blood glucose level of the user. Clearly, this device is especially suitable for monitoring glucose levels in the human body, and is especially beneficial to users having diabetes mellitus. The device and procedure may be used for other analyte materials which exhibit unique mid-IR signatures of the type described herein and that are found in appropriate regions of the outer skin.

Method for determining blood glucose levels from a single surface of the skin

Infrared ATR glucose measurement system utilizing a single surface of skin

Infrared ATR glucose measurement system (II)

Method for preparing skin surface and determining glucose levels from that surface

Self-contained method for determining blood glucose levels from an IR beam reflected from the surface of the skin

Infrared ATR glucose measurement system having an ATR with mirrored ends

Cleaning system for infrared ATR glucose measurement system (II)

An infrared heat source is directed through a chopper or modulator and beam splitter to the surface of the water. A pair of radiometers are provided, one located behind the back surface of the wafer to measure transmittance, the other adjacent to the beam splitter to measure wafer reflectance. The wafer temperature may then be calculated using an experimentally determined relationship between wafer radiance W.sub.W and wafer temperature, with wafer radiance being provided by the relationship ##EQU1## where r.sub.BS is the reflectance of the beam splitter, W.sub.W is the blackbody radiance of the wafer, W.sub.a is the blackbody radiance equivalent to ambient temperature, and e.sub.W is the wafer emittance. Alternatively, rather than locate a radiometer behind the wafer to measure wafer transmittance, a mirror may be located behind the wafer to reflect the transmitted energy back through the wafer on a periodic basis for a short part of each duty cycle. A single radiometer can then measure both the reflected and transmitted energy.

Radiometric measurement of wafer temperatures during deposition

A system for automatically controlling heating and air conditioning equipment that make up the environmental control system in a building. The system measures heat flow into and out of the building by means of an infrared sensor mounted on an inner wall and directed toward an outer wall or window. In the winter the system logic monitors the ambient temperature and if sufficient heat flow is present to allow the incoming thermo energy to heat the internal environment to the desired set point, the system directs the shut off of the furnace. In summer the system logic decides when the heat flow has decreased to a point that the air conditioning equipment can be shut down. An adjustable time delay is response to heat flow is used to compensate for rapid changes in heat flow experienced during partially cloudy days.

Infrared thermostat control

Growing community of inventors

Los Altos Hills, CA, United States of America

Herbert L Berman