Roche Diabetes Care, Inc.

Roche Diagnostics Operations, Inc.

Carl Zeiss Smt Gmbh

Carl-zeiss-smt Ag

F. Hoffmann-la Roche Ag

Herbert Fink

Joerg Dreibholz

Christoph Zaczek

Bernd Hiller

Volker Huellen

Carina Horn

Alexandra Pazidis

Julian Kaller

Jochen Schulat

Alexander Hirnet

Dieter Schmerek

Norbert Ladiges

Daniela Pfiffi

Stefan Niedermaier

Ulrich Mueller

Volker Hullen

Wolfgang Rupp

Holger Jabs

Markus Siebenhaar

Maria Dambach

Christoph Grulke

Tim Maihoefer

Volker HÜLLEN

Jörg Dreibholz

Jeffrey M Bender

Disclosed herein are methods of producing a test element for studying a body fluid sample. In the methods, a detection layer is covered with a polymeric spreading layer and applied to a support. The spreading layer can be produced by being sprayed onto the detection layer such that the spreading layer has a thickness of at most about 20 &#x3bc;m. Also disclosed are test elements produced by the methods, as well as tape cassettes incorporating such test elements.

Test elements and methods of producing the same for studying a body fluid sample

A sensor device for determining the concentration of an analyte under in-vivo conditions that includes an electrode system having an electrode with immobilized enzyme molecules and a diffusion barrier that controls diffusion from the exterior of the electrode system to the immobilized enzyme molecules. The diffusion barrier may include an aliphatic polyurethane. A process of manufacturing such a sensor device is also disclosed.

Sensor device for determining the concentration of an analyte under in-vivo conditions and process of manufacturing

A method for manufacturing a test element for detecting at least one analyte in a body fluid, a test element for detecting at least one analyte in a body fluid, a method for detecting at least one analyte in a body fluid, a system for detecting at least one analyte in a body fluid and a method for manufacturing a test element for detecting at least one analyte in a body fluid are disclosed. The method for manufacturing a test element for detecting at least one analyte in a body fluid comprises the following steps: wherein at least one hydrophilic material is applied in a manner that at least one surface section of the channel surface is covered with the hydrophilic material, wherein the surface section is adjacent to the test chemical.

Method for manufacturing a test element for detecting an analyte in a body fluid

Methods are provided for producing disposable diagnostic test elements and monitoring a property thereof, where such methods include detecting X-ray fluorescent (XRF) signals of one or more metallic components in a composite of first and second layers applied to a substrate using XRF spectrometry, determining a quantity value for each metallic component in a measured area from the XRF signals, and then calculating an areal coating quantity of the first and the second layers using the quantity values of the metallic components. Additionally or alternatively, the methods can include determining a batch specific code from the XRF signals that can be used when performing a test with a test element. Further provided are systems for monitoring a property of disposable test elements.

Methods of monitoring a property of disposable diagnostic test elements and systems incorporating the same

Methods of producing test elements for studying a body fluid sample

A method of processing an optical element which has a substrate () and a layer system () applied to the substrate (), wherein the layer system () in a starting condition has a plurality of volume defects (), wherein the method includes at least partially filling at least one of the volume defects () with a filling material (). Also disclosed is an associated method of manufacturing an optical element.

Method of processing an optical element and an optical element, in particular for a microlithographic projection exposure apparatus

A device for determining an analyte in a sample of liquid comprises an analysis apparatus configured to analyze a sample of liquid applied to an analytical area of a test element. The device comprises further an apparatus configured to prepare a surface of the analytical area by conferring hydrophilic properties to the surface. Analytes in test samples are determined by methods employing the device.

Device and method for the determination of an analyte in a sample of liquid

Described is an examination system () for locating contamination () on an optical element () installed in an optical system (), which examination system () comprises: a spatially resolving detector (); imaging optics () that magnify in particular at a magnification of between 2 times and 100 times, for magnified imaging of a surface sub-region () of the optical element () on the spatially resolving detector (); as well as a movement mechanism (), in particular a motorized movement mechanism (), for displacing the imaging optics () together with the detector () relative to the surface () of the optical element () such that any desired surface sub-region of the surface () can be imaged at magnification.

Devices and methods for inspecting optical elements with a view to contamination

Growing community of inventors

Mannheim, Germany

Herbert Fink