Wilhelm Haselmeier Gmbh & Co.

Medmix Switzerland Ag

Haselmeier Ag

B. D. Medico S.a.r.l.

Medico Development Investment Company

Medico Invest Ag

Sanofi-A Ventis Deutschland Gmbh

Herbert Bechtold

Michael Harms

Jochen Gabriel

Joachim Keitel

Daniel MacDonald

Peter Kinast

Heiko Müller

Klaus Nothdurft

Gerhard Hambrecht

Kamaal De Silva

Daniel Macdonald

Frédéric Gabriel

A dose setting mechanism is provided that includes a dose knob, a dose selector, a radial projecting rib and a snap element. The radial projecting rib is positioned circumferentially on an inside surface of the dose selector. The snap element includes a protrusion. The protruding rib has a reduced section that allows the protruding rib to move axially relative to the protrusion to initiate dose delivery.

Injection device with dose interruption fail safe

An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a fail safe feature that activates during an interrupted dose delivery event. A dose selector having a projecting rib engages a protrusion on a snap element to prevent the dose knob from moving distally if a user removes an axial force in the proximal direction during dose delivery. The dose setting mechanism can further include a reuse prevention feature.

A rotary pump is presented for use in a medicament delivery device, where the pump has a back plate having an inner surface and a rotor housing is positioned adjacent to the back plate having a peripheral wall. A front plate support is connected to the back plate and a flexible front plate is positioned between the front plate support and the rotor housing. The pump is rotated using a planetary gear transmission, where an eccentric shaft is operatively connected to the planetary gear mechanism. A rotor is rotationally fixed to the eccentric shaft and movably positioned within the rotor housing. The rotor has three lobes, where each lobe has two peripheral curved surfaces sharing a common apex, where a first portion of each peripheral surface adjacent to the apex defines a non-smooth curve.

Rotary pump driven medicament delivery device

An injection device includes a housing having a receptacle for a vessel for holding injection fluid; an operator-manipulated element for setting an injection dose; a dosing member rotatable about a longitudinal center axis relative to the housing when setting the injection dose; a feed part; and, a latching unit acting between the feed part and housing. The dosing member has a zero position whereat no dose is set and an injection position whereat an intended dose of injection fluid is set. A spring acts between the dosing member and the housing to return the dosing member from an intermediate position to the injection position or a zero position.

Injection device

An injection device has a housing ( ) in which a container ( ) for receiving an injectable fluid ( ) is longitudinally movable. To its proximal end, an injection needle ( ) can be releasably coupled. The injection device has a spring ( ) associated with a releasable detent ( ) for latching this spring ( ) in a cocked configuration (FIG. ). Further, there is a cocking member ( ) insertable into the proximal end of the housing ( ) for moving the longitudinally movable container ( ) in the distal direction and for thereby bringing the spring ( ) into the cocked configuration.

Injecting device

The invention relates to an injection device (,) having a housing (,) and an injection fluid container (,) which can move, in relation to this housing, between a distal and proximal end position, and also having a pushrod (,) to act on a plunger (,) in this container (,) for the purpose of expelling fluid from the container. A drive connection (,) is provided between the pushrod (,) and the container (,) and, in the distal end position of the container, this drive connection is effective in both the proximal and the distal direction, but in the proximal end position of the container (,), it is only effective when the pushrod (,) is moved in the distal direction.

An injection device (10) is adapted to receive a cartridge (11) holding injection fluid (12). This cartridge (11) is displaceable in the proximal direction in the injection device counter to the force of a resetting spring (157). An adjustable-length tappet (80) is biased in the proximal direction by a spring (53), is displaceable in the injection device between a proximal end position and a distal end position, and has a threaded spindle (19) which is guided in the thread (17) of an adjusting member (15), serves to act upon a plunger (23) provided in the cartridge (11), and has a guide member (67) associated with it; the guide member is connected to it in a manner fixed against relative rotation but axially freely displaceably. This guide member (67) is rotatable relative to the housing (100) of the injection device (10) in the distal end position of the tappet (80), but not in the proximal end position thereof.

To permit accuracy presetting of a dose for an injection to be ejected from an ampule (12) containing more fluid medication than the dose requires, a plunger (18) which is telescopically received within a tubular element (77) is movable against the customary piston (17) in the ampule for a distance which depends on the extent of telescopic insertion of the plunger stem (18') within the tubular element (77). This extent can be set by a rotary knob or sleeve (56, 65) which rotates the tubular element with respect to the plunger (18); the plunger and tubular element are coupled together by a steeply pitched spiral thread (76), thereby controlling the extent of projection of the combined injection dosing arrangement of plunger (18) and plunger length setting mechanism (77), and hence controlling the amount of medicinal fluid expelled through an injection needle (16) coupled to the ampule (12) at the end of the injection device.

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Denkingen, Germany

Herbert Bechtold