The Johns Hopkins University

Greatbatch Ltd.

Other

Zoll Circulation, Incorporated

Zoll Medical Corporation

Surgi-vision Inc.

Revivant Corporation

Siemens Healthcare Gmbh

Mri Interventions, Inc.

Cardiologic Systems, Inc.

Henry R Halperin

Albert Clark Lardo

Robert A Stevenson

Ronald David Berger

Warren S Dabney

Robert Shawn Johnson

Holly Noelle Moschiano

Ergin Atalar

Kishore Kumar Kondabatni

Christine A Frysz

Scott Brainard

Christopher Michael Williams

Elliot R McVeigh

Darren R Sherman

Buehl E Truex

James Adam Palazzolo

Daniel Robert Kaiser

Hugh Calkins

Joao Lima

Harikrishna Tandri

David George Hunter

Leslie Tung

Gary A Freeman

Paul Arthur Bottomley

Norman Alan Paradis

David Barash

Elliott R McVeigh

Barry C Muffoletto

Scott W Kelley

Joshua E Tsitlik

Seth Weinberg

Ronald D Watkins

Mark Gelfand

Randy W Westlund

Richard L Brendel

Parag V Karmarkar

Natalia A Trayanova

Jeff Fleigle

Christine McNamara

Myron L Weisfeldt

Xiaoming Yang

Joseph L Allain

Hermenegild Arevalo

Ehud J Schmidt

Jason Constantino

Tommaso Mansi

Neil Samuel Rothman

Bin Lou

Neal N Nesselbeck

Julian Krebs

Joseph E Spaulding

Robert Charles Susil

Menekhem Muz Zviman

Kreg George Gruben

Arkadiy Tsitlik

Aravindan Kolandaivelu

Hiroshi Ashikaga

Robert Susil

Howard Levin

Jeff Koepsell

Nathaniel M Fried

Gwyneth Susil

Steve Tulley

Holly Noelle Mosciano

Alan Cheng

Hugh Caikins

Katherine Chih-ching Wu

Elias Zerhouin

Elliott R Mcveigh

Christine Enger Mcnamara

Elliot R Mcveigh

James A Palazzolo

Elliot Mcveigh

Robert C Susil

An embodiment in accordance with the present invention provides a catheter solution that would maintain MRI-compatible metallic braiding or metallic covering on a surface of the catheter, and that also prevents cables disposed in an interior lumen of the catheter from effectively propagating currents induced from external signal transmissions, which could cause a rise in temperature of the cables themselves and of tissues surrounding the catheter. The present invention uses metals which are non-ferromagnetic and not highly paramagnetic, so they do not cause large susceptibility artifacts in the MRI field. The construction of the braid prevents most of the RF fields from penetrating into the anterior of the catheter. Therefore, there is no need or a reduced need to add heat amelioration components to each electrical cable inside the catheter.

MRI radio-frequency heating amelioration for metallic braided catheters

A magnetic-resonance-imaging-compatible (MRI-compatible) cardiac defibrillator includes: a defibrillator generator; first and second electric wires, each being electrically connected to said defibrillator generator; first and second defibrillation pads, each being electrically connected to a respective one of said first and second electric wires; and a low pass filter electrically connected between said defibrillator generator and said first and second electric wires to prevent a noise in an MRI image caused by a radiofrequency interference from the defibrillator as well as protect a patient and the defibrillator from MRI radiofrequency imaging signals, wherein said low pass filter has a cutoff frequency set such that differential mode noise at an MRI Larmor frequency is in an attenuated band while a system-test signal by said defibrillator generator is in a pass band of said low pass filter.

MRI-compatible cardiac defribrillator

A method of planning a patient-specific cardiac procedure according to an embodiment of the current invention includes receiving three-dimensional imaging data of a patient's heart, simulating at least one of electrophysiological or electromechanical activity of at least a portion of the patient's heart using the three-dimensional imaging data, and planning the patient-specific cardiac procedure based on the simulating. The cardiac procedure is for providing a preselected alteration of at least one of electrophysiological or electromechanical behavior of the patient's heart.

System and method for planning a patient-specific cardiac procedure

The present invention provides both methods and devices for termination of arrhythmias, such as ventricular or atrial tachyarrhythmias. The device and method involves application of alternating current (AC) for clinically significant durations at selected therapeutic frequencies through the cardiac tissue to a subject experiencing arrhythmia. Methods are also provided to minimize or eliminate pain during defibrillation.

Method and device for treating cardiac arrhythmias

A system for improving cardiac output of a patient suffering from pulseless electrical activity or shock and yet displays myocardial wall motion including: a sensor to detect myocardial activity to determine the presence of residual left ventricular pump function having a contraction or ejection phase and a filling or relaxation phase, a device to prompt the application of or apply a compressive force repeatedly applied to the chest based on the sensed myocardial activity such that the compressive force is applied during at least some of the ejection phases and is ceased during at least some of the relaxation phases to permit residual cardiac filling, thereby enhancing cardiac output and organ perfusion.

Non-invasive device for synchronizing chest compression and ventilation parameters to residual myocardial activity during cardiopulmonary resuscitation

Systems and methods for personalized sudden cardiac death risk prediction that generates fingerprints of imaging features of cardiac structure and function. One or more fingerprints and clinical data may be used to generate a risk score. The output risk score may be used to predict the time of death in order to select high-risk patients for implantable cardioverter-defibrillator treatment.

Risk prediction for sudden cardiac death from image derived cardiac motion and structure features

An embodiment in accordance with the present invention provides an improved electrically conductive transmission line that is radio frequency (RF) safe. The present invention does not include any inductive coupling elements. Instead, multiple coils constructed from twisted pairs of wires are used to block the common mode of the received magnetic resonance (MR) signal that can cause heating, while passing the differential mode that is used for tracking and/or imaging. These twisted pair coils are easily manufactured out of a single length of twisted pair wire, but multiple segments could also be used. The twisted pair coils of the present invention are easier to manufacture than the pre-existing inductive coupling element-based transmission lines, and occupy less overall volume inside a medical device. The individual coils of twisted pairs are tuned to the resonant frequency of the MR scanner by the addition of appropriate capacitors.

RF safe transmission line for MRI

MRI-compatible cardiac defibrillator

A method of processing a raw acceleration signal, measured by an accelerometer-based compression monitor, to produce an accurate and precise estimated actual depth of chest compressions. The raw acceleration signal is filtered during integration and then a moving average of past starting points estimates the actual current starting point. An estimated actual peak of the compression is then determined in a similar fashion. The estimated actual starting point is subtracted from the estimated actual peak to calculate the estimated actual depth of chest compressions. In addition, one or more reference sensors (such as an ECG noise sensor) may be used to help establish the starting points of compressions. The reference sensors may be used, either alone or in combination with other signal processing techniques, to enhance the accuracy and precision of the estimated actual depth of compressions.

System for determining depth of chest compressions during CPR

The present invention is directed to a system and method for reducing large magnetic artifact susceptibility in magnetic resonance imaging. The present invention is used to maximize cancellation of the magnetic field distortion cremated when objects with high variations in magnetic susceptibility are placed in a uniform magnetic field. Particularly, the present invention reduces the magnetic resonance imaging artifact produced by pacemakers and internal cardiac defibrillators in order to maximize the diagnostic image quality in the region surrounding these devices.

Device for cancellation of large magnetic susceptibility artifacts in magnetic resonance imaging of patients with pacemakers and implantable cardiac defibrillators

Growing community of inventors

Pikesville, MD, United States of America

Henry R Halperin