Isco, Inc.

Teledyne Isco, Inc.

Teledyne Instruments, Inc.

Henry L Walters

Robert W Allington

Daniel G Jameson

Yoossef Tehrani

Frederick Alan Nabity

Robert R Fiedler

Dale L Clay

Scott L Blakley

Dale Messer

Dale A Davison

To provide a protective coat on a refrigerated sample collector for a corrosive environment a unitary frame includes a support unit with condenser and evaporator coils mounted to the support unit and an orifice connecting the condenser and evaporator coils. The evaporator coils, condenser coils and a restrictor are powder coated after being connected, whereby an effective seal is provided for the restrictor, condenser coils and evaporator coils after they are assembled to the support. The unitary frame can be easily removed or connected as a unit to the sample collector. The bottle rack for the sample collector is made by injection molding two halves of the rack each of which has a matching surface and a bottle positioning surface. The matching surfaces are fastened together by placing the matching surfaces together back to back whereby locating members are spaced apart a sufficient distance.

Sample collector and components thereof

To provide a protective coat on a refrigerated sample collector for a corrosive environment a unitary frame includes a support unit with condenser and evaporator coils mounted to the support unit and an orifice connecting the condenser and evaporator coils. The evaporator coils, condenser coils and restrictor are powder coated after being connected, whereby an effective seal is provided for the restrictor, condenser coils and evaporator coils after they are assembled to the support. The unitary frame can be easily removed or connected as a unit to the sample collector. A peristaltic pump may be used for drawing at least one sample into the refrigerated sample collector and depositing said sample into at least one sample bottle. The peristaltic pump may include contoured tube guides to reduce movement of the peristaltic pump as a roller paddle rotates.

To provide a protective coat on a refrigerated sample collector for a corrosive environment a unitary frame includes a support unit with condenser and evaporator coils mounted to the support unit and an orifice connecting the condenser and evaporator coils. The evaporator coils, condenser coils and a restrictor are powder coated after being connected, whereby an effective seal is provided for the restrictor, condenser coils and evaporator coils after they are assembled.

Pumping requirements for chromatograph applications are for constant flow at high and variable pressures and for accurate programmable control of liquid composition. A two-cylinder pump, pumping system, and associated controls provide an accurate, fixed flow rate. A low pressure gradient former controls composition. During the initial portion of the pumping stroke of a first piston in which fluid is being compressed due to its finite bulk modulus of elasticity its check valve remains closed, a second piston provides all the flow required at a fixed rotational speed. Then, once the first piston has reached its bottom dead center, the control system switches to a constant-pressure control mode, thereby maintaining the flow rate at a fixed value. Constant-pressure control is again switched off either when the second piston's discharge check valve closes, or when the second piston's inlet check valve opens, and pump control returns to fixed rotational speed. Determining the angular displacement at which to effect these control-mode switches is carried out by monitoring the discharge pressure and storing the values of the angular displacement at which the first temporal derivative of pressure changes rapidly. The invention provides novel arrangement for synchronizing the gradient generator by equating recompression volume to recompression volume of the high pressure pump.

High pressure reciprocating pump and control of the same

Pumping for chromatograph applications calls for constant flow at high pressures and for accurate control of liquid composition. A two-cylinder pump, and associated controls provide an accurate, fixed flow rate. During the initial portion of the pumping stroke of a first piston, while its check valve remains closed, a second piston provides all the flow required at a fixed rotational speed. Once the pressure inside the first piston's cylinder has reached that of the discharge and its discharge check valve opens, the control system switches to a constant-pressure control mode, to maintain a fixed flow rate. Constant-pressure control is switched off when the second piston's discharge check valve closes, and pump control returns to fixed rotational speed. Determining the angular displacement at which to effect these control-mode switches is carried out by monitoring changes in the discharge pressure.

A multiple chamber sample holding cartridge is used with a supercritical fluid extractor that causes membranes dividing the cartridge into chambers to rupture upon the pressurization of the sample cartridge, thereby allowing the intermixing of materials contained in the chambers. The neutral oil and loss determination of soybean and other oilseed oils by supercritical fluid extraction is efficient with this two-chambered sample cartridge.

Multi-chambered supercritical fluid extraction cartridge and processes using it

A variable-orifice fluid restrictor for use with a supercritical extractor or chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe is disposed toward the inlet line. The distal end of the probe includes an adjustable orifice means adapted for metering the fluid and having first and second orifice members and an adjusting stem having first and second ends. The adjustable orifice means is adjacent to the outer surface of the probe and the orifice means is adjustable with the adjusting stem. The end of the adjusting stem is located at the distal end of the probe and is adapted for moving the first orifice member with respect to the second orifice member to control the adjustable orifice for varying the restriction of fluid passing through the adjustable orifice. The distal end of the probe is inside the collector and the adjusting stem extends outside of the collector.

Apparatus and method for supercritical fluid extraction or supercritical fluid chromatography

A variable-orifice fluid restrictor for use with a supercritical extractor or chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe is disposed toward the inlet line. The distal end of the probe includes an adjustable orifice means adapted for metering the fluid and having first and second orifice members and an adjusting stem having first and second ends. The adjustable orifice means is adjacent to the outer surface of the probe and the orifice means is adjustable with the adjusting stem. The end of the adjusting stem is located at the distal end of the probe and is adapted for moving the first orifice member with respect to the second orifice member to control the adjustable orifice for varying the restriction of fluid passing through the adjustable orifice.

Apparatus and method for supercritical fluid extraction or supercritical

An automatic variable-orifice fluid restrictor for use with a supercritical extractor having a collection trap or a supercritical chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe carries an inlet connected to the inlet line and is outside of the trap. The distal end of the probe includes a variable orifice means adapted for metering the fluid. The variable orifice means is adjacent to the outer surface of the probe and is located in the midst of the trap. The variable orifice means is adjusted by an adjusting stem having first and second ends. The first end of the adjusting stem is connected to automatic control means such as a servo at the proximal end of the probe and outside of the trap. The second end of the adjusting stem varies the area of the orifice by moving a first orifice member. The stationary second orifice member cooperates with the first orifice member to form the orifice. The first orifice member moves axially when the orifice is closed and moves both axially and rotationally when the orifice is open or partially open. This cleans deposits from the orifice without damaging the orifice parts by high pressure notional physical contact.

Multi-chambered supercritical fluid extraction cartridge

A preparatory supercritical extraction cartridge includes a chamber for sample having a volume in the range of 20 cubic centimeters to 2,000 cubic centimeters. An inlet and an outlet are fastened to the cartridge walls by threads and sealed to said cartridge walls With spring loaded seals so that they can be removed with a torque requirement of less than 35 pound inches. Inlet and outlet tubing are fastened to the inlet and outlet by quick release connectors.

Growing community of inventors

Lincoln, NE, United States of America

Henry L Walters