New York University

American Biosciences, Inc.

The United States of America As Represented by the Secretary of

The United States of America As Represented by the Department of Health

National Institutes of Health

Henry I Huang

Paul L Huang

Sylvia Lee-Huang

Peter Huang

Philip L Huang

Hao-Chia Chen

Hsiang-fu Kung

Peter L Nara

A new protein, termed TAP 29, obtainable from the root tuber of the plant Trichosanthes kirilowii or produced by recombinant means is useful for treating HIV infections or tumors. In treating HIV infections, the protein is administered alone or in conjunction with conventional AIDS therapies. Also provided are processes for purifying the protein, DNA sequences encoding the protein, hosts expressing the protein, recombinant DNA methods for expressing the protein, and antibodies specific for the protein.

Anti-HIV protein, TAP 29, from tricosanthes, DNA coding therefor and

A protein, in particular MAP 30, obtainable from both the fruit and seeds of Momordica charantia or produced by recombinant means useful for treating tumors and HIV infections is disclosed. In treating HIV infections, the protein is administered alone or in conjunction with conventional AIDS therapies. Also provided are processes for purifying the protein, DNA sequences encoding the protein, and recombinant DNA methods for expressing the protein.

Plant protein useful for treating tumors and HIV infection

New proteins, termed GAP 31, obtainable from the seeds of Gelonium multiflorum, and DAP 30 and DAP 32, obtainable from the leaves or seeds of Dianthus caryophyllus, or the above proteins produced by recombinant means, are useful for treating HIV infections. In treating HIV infections, the protein is administered alone or in conjunction with other anti-HIV therapeutics. Also provided are processes for purifying the proteins, DNA sequences encoding the proteins, hosts expressing the proteins, recombinant DNA methods for expressing the proteins, and antibodies specific for the proteins.

Anti-HIV proteins GAP 31, DAP 30 and DAP 32 and therapeutic uses thereof

Growing community of inventors

New York, NY, United States of America

Henry I Huang