The Immune Response Corporation

Life Technologies Corporation

Henry C Chiou

Jeffrey L Rogers

Dennis J Carlo

Chao Yan Liu

Jingqiu Li

Meredith Jones

Sanjay K Vasu

Maria Cisneros

Jeffrey Rogers

A molecular complex comprising a gene encoding interferon releasably linked to a conjugate of a nucleic acid binding agent and a ligand which binds to a component on the surface of a cell. In a preferred embodiment, the gene encodes human IFN-&agr;, IFN-&bgr;, or IFN-&ggr;. The complex can be used to obtain targeted expression of interferon in selected cells either in vivo or in vitro.

Targeted delivery of genes encoding interferon

A molecular complex comprising a gene encoding interferon releasably linked to a conjugate of a nucleic acid binding agent and a ligand which binds to a component on the surface of a cell. In a preferred embodiment, the gene encodes human IFN-.alpha., IFN-.beta., or IFN-.gamma.. The complex can be used to obtain targeted expression of interferon in selected cells either in vivo or in vitro.

Growing community of inventors

Encinitas, CA, United States of America

Henry C Chiou