Other

Københavns Universitet

Fida-tech Aps

Larsen, Claus Selch

Henrik Jensen

Jesper Langgaard Kristensen

Claus Selch Larsen

Mette Agergaard Thing

Susan Weng Larsen

Jesper Ostergaard

Jesper Østergaard

Johan Peter Bøtker

Claus Cornett

Jukka Rantanen

Adam Bohr

An inhaler or add-on device for an inhaler for dispensing a medicament to be inhaled. The inhaler or add-on device has a housing (H) with an air inlet (A_I), and an air outlet (A_O) for outputting air to be inhaled by a user. The housing (H) defines a flow path (FP) between the air inlet (A_I) and air outlet (A_O), and a passive acoustic element (PAE) is arranged in this flow path (FP) inside the housing (H). The passive acoustic element (PAE) has a structure having one or more structured gaps arranged to be passed by an air flow and it is dimensioned such that air flow passing it will generate sound (S) with pre-determined characteristics depending on the air flow speed. This allows acoustic monitoring of air flow passing the first passive acoustic element (PAE) external to the housing (H) by capturing and processing sound generated.

Inhaler with acoustic flow monitoring

The present invention relates to a compound of formula (I):   

Imidazole derivatives as prodrugs of diclofenac

The present invention relates to a compound of formula (I): wherein Ris R-IPU and Ris the acyloxy residue of diclofenac or naproxen, and specified by the following structures (A) wherein OH&#x2014;R-IPU is selected from (B) and Rand Rmay be the same or different selected from (C) and salts, solvates and hydrates thereof. 

Prodrugs of naproxen and diclofenac

The present invention relates to novel depot formulations (prodrugs) comprising an immobility promoting unit linked via an ester to an active pharmaceutical ingredient, i.a. common NSAIDs. The novel depot formulations are suitable for intra-articular injections and are soluble at slightly acidic pH to facilitate ease of injection, and sparingly soluble at physiological pH thereby precipitating at the site of administration. The precipitate will slowly dissolve and the active drug is released from dissolved depot formulation following esterase mediated cleavage of the ester link between the immobility promoting unit and the active pharmaceutical agent.

Prodrugs of non-steroid anti-inflammatory agents (NSAIDS)

A method for quantitative characterization of non-covalent interactions and analyte quantification in nanoliter samples is described. The procedure is based on Flow Induced Dispersion Analysis (FIDA), of which the only system requirements is a narrow tube, capillary or channel equipped with a detector. The technique can be implemented using standard equipment such as High Performance Liquid Chromatography (HPLC), Flow Injection Analysis (FIA) or Capillary Electrophoresis (CE).

Analyte quantification using flow induced dispersion analysis

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Roskilde, Denmark

Henrik Jensen