Nederlandse Organisatie Voor Toegepast-natuurwetenschappelijk Onderzoek Tno

Henricus Matheus Wilhelmus Maria Thijssen

Roy Christiaan Montijn

Frank Henri Johan Schuren

Theodoor Maximiliaan Slaghek

Johannes Wilhelmus Timmermans

Johannes Wilhelmus Leonardus Boumans

Jacobus Johannes Frederik Van Veen

Jacobus Johannes Frederick Van Veen

This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing antdaries or flavoring compounds and for pharmaceutical and/or nutraceutical applications.

Inducible release vehicles

This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in an applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing anti-caries or flavoring compounds and for pharmaceutical and/or nutraceutical applications.

The invention relates to a method of detecting pathogenicstrains by hybridizing genomic DNA of a sample suspected to containto two or five specific sequence markers, as identified by MARKER NO. 1 through MARKER NO. 5 or homologues thereof. The invention further relates to a kit of parts comprising an array and reference materials for performing a method of the invention.

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The invention relates to the field of antibiotic compositions, both inside and outside the medical field. Presented is a new class of antibiotic compounds around the lead compound (3,4-dichloro-phenyl)-carbamic acid 2-isobutoxycarbonylamino-1-methyl-ethyl ester, which are especially useful for combating infections with gram-positive bacteria and especially MRSA.

Carbamate antibiotics

The invention relates to the field of antibiotic compositions, both inside and outside the medical field. Presented is a new class of antibiotic compounds, the bis(1-aryl-5-tetrazolyl)methanes, which are especially useful for combating infections with gram-positive bacteria and especially MRSA.

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Houten, Netherlands

Henricus Matheus Wilhelmus Maria Thijssen