Therasense, Inc.

Pepex Biomedical, Inc.

Henning Sakslund

James L Say

Michael F Tomasco

Adam Heller

Hyun Brian Cho

Jay Douglas Audett

Duane O Yamasaki

Nathan R Long

Eric A Peper

An in vivo electrochemical sensor including a working electrode, and an analyte-responsive sensing layer proximate the working electrode. The sensing layer is exposed at an edge of the sensor, wherein the sensor signal is limited, at least in part, by mass transport of analyte to the sensing layer. The sensor is configured and arranged for implantation into the body of a mammal for contact with body fluids of the mammal. The analyte diffuses to the sensing element via the edge of the sensor, thereby restricting mass transport of the analyte to the sensing element. This is because the solution-contacting surface area of the sensor edge is much smaller than an open face of the sensing layer.

Mass transport limited in vivo analyte sensor

The present disclosure relates to a sensor including a bundle of electrically conductive fibers. The sensor also includes a sensing material coating at least some of the fibers in the bundle, and an insulating layer that surrounds the bundle of electrically conductive fibers.

Sensor for measuring a bioanalyte such as lactate

The present disclosure relates to an on-line lactate sensor arrangement. The sensor arrangement includes a lactate sensor, a catheter for withdrawing a test sample, and a first fluid flow line provided fluid communication between the lactate sensor and the catheter. The sensor arrangement also includes a source of sensor calibration and anticoagulant solution, and second fluid flow line providing fluid communication between the source of sensor calibration and anticoagulant solution and the lactate sensor.

System and method for measuring a bioanalyte such as lactate

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Pleasant Hill, CA, United States of America

Henning Sakslund