Roche Diagnostics Operations, Inc.

Roche Operations Ltd.

Ventana Medical Systems, Inc.

Roche Diabetes Care, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Nigel A. Surridge

David W. Burke

Henning Groll

Michael J Celentano

Steven Jerome Moore

David W Burke

Raghbir Singh Bhullar

Frank A Chan

Harvey B Buck, Jr

Nigel A Surridge

Craig Ian Wightman

James L Pauley

Brian Howard Kram

Glen Ward

Matthew Mette

Christine Tse

Benjamin David Randall

Daniel O'Connor

Kayla Capps

Ken Stumpe

Troy Paluszcyk

Ali Mousavi

Douglas Paul Walling

John T Austera

Timothy L Ranney

Raymond T Kozikowski, Iii

Eric L Klein

Melinda Polaske

Austin Micheil Ashby

Edward E Durrant

Simon Jonathon Spence

Kevin David Marshall

Matthew Ketterer

Casey A Kernag

Georgeta C Lica

Benjamin James

Kevin Talucci

Charles H Weidner

Jessica Jones

Melis Hazar

Chana R Paluszcyk

Raviraj Thakur

Jessica A Wifall

Mirek Holubec

Kenneth S Weir

Timothy I Ranney

Joseph A Finnerty

Lizhen Pang

Bryan Barnes

Andrew Watkins

Sacha Dopheide

Patrick Brown

Kenneth Weir

Matthew D Mette

Daniel O`CONNOR

Jr James L Pauley

Joseph Finnerty

Douglas P Walling

Jr Buck Harvey B

Georgeta Lica

Thomas Walker

Mattew Carlyle Sauers

Steven K Moore

Mindy Polaske

Iii Kozikowski Raymond T

Melinda J Polaske

Daniel O`connor

Raghbie S Bhullar

David Cottle

Devices and methods for the deposition of reagents onto cells or tissue samples are disclosed. Also disclosed are reagent compositions suitable for dispensing via a droplet-on-demand system.

Inkjet deposition of reagents for histological samples

Automated system configured to perform and methods for performing one or more slide processing operations on slides bearing biological samples. The system and methods enable high sample throughput while also minimizing or limiting the potential for cross-contamination of slides. The automated systems can include features that facilitate consistency, controllability of processing time, and/or processing temperature.

Automated histological processing of biological specimens and associated technology

Methods and compositions for removing precipitates or reducing the formation of precipitates generated in hematoxylin solutions. The methods and compositions feature cleaning solutions that feature chemical compounds that initiate processes including but not limited to acidification of the waste solution, chelation of metal ions in the waste solution, reduction reactions, oxidation reactions, and metal salt addition reactions.

Methods and compositions for removing or reducing formation of precipitates generated in hematoxylin solutions

A specimen processing system is capable of processing specimens carried on slides. The specimen processing system can sequentially deliver slides and opposables to specimen processing stations. The specimen processing stations can use the opposables to apply a series of liquids to the specimens. The applied liquid can be moved along the slide using capillary action while the specimen processing stations control the processing temperatures.

Specimen processing systems and methods for aligning slides

The present invention provides a test strip for measuring a signal of interest in a biological fluid when the test strip is mated to an appropriate test meter, wherein the test strip and the test meter include structures to verify the integrity of the test strip traces, to measure the parasitic resistance of the test strip traces, and to provide compensation in the voltage applied to the test strip to account for parasitic resistive losses in the test strip traces.

System and method for quality assurance of a biosensor test strip

A blood glucose management device is operable to seamlessly provide a sequence of at least two displays of data relating to one or more blood glucose measurements to a user, upon minimal user interaction, with the blood glucose management device.

Blood glucose management and interface systems and methods

The present invention provides a system of biosensors whose dose-response curves are maintained within a predetermined and desired range or tolerance during production by selecting a feature of the biosensors that can be varied during production. For example, in one exemplary embodiment the effective area of the working electrode of an electrochemical biosensor can be varied during production as needed to offset variations that occur, e.g., in the reagent of the biosensors as production proceeds. In another exemplary embodiment, the dose-response curve of biosensors not yet produced can be predicted and one or more features of these biosensors can be selected to maintain the dose-response curve within a predetermined range or tolerance.

Biosensor with predetermined dose response curve and method of manufacturing

A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.

System and method for analyte measurement using dose sufficiency electrodes

The present invention provides a test strip for measuring a concentration of an analyte of interest in a biological fluid, wherein the test strip may be encoded with information that can be read by a test meter into which the test strip is inserted.

System and method for coding information on a biosensor test strip

A connector for establishing electrical connection between a testing device and a test strip with a biological fluid thereon includes a contact pad on the test strip, and one or more contact wires in the testing device. When the strip is inserted into the testing device, part of the strip's end engages a contact portion of a contact wire and deflects it in a direction normal to the direction of insertion. In certain embodiments the radius of curvature (in the direction of insertion) of the contact portion is controlled to reduce abrasion of the strip by the wire. In other embodiments the radius of curvature (perpendicular to the direction of insertion) is controlled to reduce the abrasion of the strip by the wire. Sometimes the contact portion and/or contact pad is plated with a sacrificial material to reduce the coefficient of friction. In other embodiments various numbers of contacts receive the end of the strip substantially simultaneously, or are staggered in rows to distribute the resistance presented.

Biological testing system and connector therefor

Growing community of inventors

Indianapolis, IN, United States of America

Henning Groll