Fresenius Ag

Henning Brass

Stefan Kreber

Artur Meisberger

Wolfgang Biesel

Wolfram Weber

Friedrich Witthaus

Carlo Lay

Arthur Meisberger

Friederich Witthaus

Johannes Geibel

A centrifuge, especially a flow-through centrifuge free of rotating seals, for centrifuging biological fluids has a stand on which a frame (,) is rotatably mounted. A centrifuge chamber (,) is rotatably mounted on the rotating frame (,) to rotate about the axis of the latter. The centrifuge chamber (,) is driven in the same direction of rotation as the frame (,) but at twice the rotational speed. Coupling elements which are engaged by magnetic forces and are designed in the manner of a clutch disk or a gearwheel are used to transmit the torque to the centrifuge chamber or the rotating frame. Force is transmitted in a non-contact and wear-free manner. No lubrication is necessary, which also reduces the buildup of dust and dirt. In addition, there is little generation of noise.

Flow-through centrifuge for centrifuging biological fluids

A centrifuge has a drive unit, a separation chamber which can be inserted into the drive unit, and a scanning device for recognizing the position of the separation chamber which is rotated by the drive unit. The separation chamber is constructed as a disposable chamber and is provided with a marker element which is arranged in a scanning region extending annularly around the rotation axis of the chamber. The position of a phase boundary window is detected by sensing the position of the marker with a phase boundary detector portion of the scanning device whereby the chamber can be inserted into the drive unit in any position.

Centrifuge having marker elements

The invention concerns a process and a device for more efficiently obtaining a highly pure fraction of thrombocytes during density centrifugation of blood, which no longer has to be filtered before infusion into a patient for leukocytes contained therein, in order to prevent immunization of the recipient. The invention is based on a two-stage density separation, wherein in a first stage a separation is made between cells and thrombocyte-rich plasma, and the thrombocyte-rich plasma is not separated into a thrombocyte concentrate and thrombocyte-poor plasm until a second stage. During the first separation, the position of the phase boundary is changed cyclically in the first separation stage. Through alternating the phase boundary in the first stage, it becomes possible for the first time in the second stage to obtain highly pure thrombocyte concentrations with minimally low leukocyte contamination from the transferred thrombocyte-rich plasma without loss of efficiency.

Method and apparatus for the separation of blood into its components

A separation device with a transparent separation chamber, whereby a direct light source illuminates the components to be separated and the individual components reflect the light intensity as a function of their individual coloring (brightness) via optics onto a linear group of photodetectors. The signals received by the detectors are forwarded to a computing unit in which they are processed. A regulating unit, which operates very precisely due to the accuracy and the high speed of the receiver and computing unit, is controlled according to a program and thus assures optimum separation performance of the separation device.

Growing community of inventors

Homburg, Germany

Henning Brass