Ablynx N.v.

Hendrik Adams

Johannes Joseph Wilhelmus De Haard

Michael John Scott Saunders

Christophe Blanchetot

Catelijne Stortelers

Peter Vanlandschoot

Francis Descamps

Maria Gonzalez Pajuelo

Regorius Leurs

Philippe Van Rompaey

Pascal Gerard Merchiers

Martine Smit

Maarten Van Roy

Sven Jähnichen

David Andre Baptiste Maussang-Detaille

The present invention relates to amino acid sequences that are directed against G-protein coupled receptors (GPCRs), as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The invention also relates to nucleic acids encoding such amino acid sequences and; to methods for preparing such amino acid sequences and polypeptides; to host cells expressing or capable of expressing such amino acid sequences or polypeptides; to compositions, and in particular to pharmaceutical compositions, that comprise such amino acid sequences, polypeptides, nucleic acids and/or host cells; and to uses of such amino acid sequences or polypeptides, nucleic acids, host cells and/or compositions, in particular for prophylactic, therapeutic or diagnostic purposes.

Amino acid sequences directed against GPCRS and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders

Growing community of inventors

Rotterdam, Netherlands

Hendrik Adams