Metrohm Ag

Helwig Schafer

Wolfgang Frenzel

Paul Zahner

In order to regenerate a plurality of suppressors (6, 6a, 6b) that are inserted alternatingly into a device for ion-exchange chromatography, apart from an analysis branch (9), at least one additional treatment branch (10, 10a) is anticipated, through which a treatment agent (7, 7a) can be fed. The analysis branch (9) and the treatment branch (10, 10a) each possess a gap (34) in which the suppressors (6, 6a, 6b) can be alternatingly inserted. In order to insert a suppressor in a pipework branch, the suppressor is moved relative to the pipework branch until the connection openings (36a, 36b) of the suppressor are aligned with the corresponding pipe openings (35) of the gap of the pipework branch concerned.

Device for ion-exchange chromatography and method of cyclically

From an analysis probe to be analyzed, impurities such as proteins or solid matter are separated from the analytes to be analyzed by way of dialysis. An analysis solution containing the analytes is separated from an acceptor solution by a membrane of a dialysis cell. The membrane is chosen such that the analytes diffuse from the analysis solution through the membrane into the acceptor solution. In order to maintain as high as possible concentration of analytes in the acceptor solution, the analysis solution is constantly renewed. The acceptor solution remains stationary in an acceptor chamber until the concentration of analytes in the acceptor solution has reached a predetermined value, for example 95%.

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Herisau, Switzerland

Helwig Schafer