Commonwealth Scientific and Industrial Research Organisation

Helmut Werner Thissen

Richard Alexander Evans

Graham M Johnson

Paul Pasic

Laurence Meagher

Aylin Koegler

Berkay Ozcelik

Richard Evans

Berkey Ozcelik

The application is directed to polymer coatings which can be modified to control biointerfacial interactions including biofilm formation and protein adsorption onto said coatings. The polymer coatings comprise a First Component comprising epoxide or alkenyl groups, and a Second Component comprising at least one amine group. The polymer coatings further comprise at least one bioactive agent which may control said biofilm formation and/or protein adsorption. Also disclosed herein are methods for producing said coatings incorporating bioactive molecules in one or two step procedures on a substrate. The polymer coating may be immobilised on the substrate via the reaction of functional groups present on the First Component and/or Second Component with complimentary functional groups disposed on at least one surface of the substrate.

Polymer coatings

The present invention provides a process of coating at least a portion of a substrate surface comprising contacting the surface with hydrogen cyanide monomeric units under conditions permitting polymerisation of the hydrogen cyanide monomeric units to form a polymer that coats the surface. Also provided is a substrate coated by a polymer according to the claimed process. Also provided is a method of forming a hydrocyanic acid-based hydrogel, the method comprising co-polymerisation in a solution, the solution comprising hydrogen cyanide monomer units and co-monomers.

Hydrogen cyanide-based polymer surface coatings and hydrogels

The present invention relates to a controllable polymeric surface coating including a macromolecule, which is covalently bound to the surface of a substrate, the macromolecule including a plurality of polymerization initiators and a plurality of surface binding groups. Pendant polymers may be grafted from at least some of the polymerization initiators.

Polymeric coatings and methods for forming them

The present invention relates to a controllable polymeric surface coating including a macromolecule, which is covalently bound to the surface of a substrate, the macromolecule including a plurality of polymerization initiators and a plurality of surface binding groups; and pendant polymers grafted from at least some of the polymerization initiators.

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Rowville, Australia

Helmut Werner Thissen