Jenavalve Technology Gmbh

Tricares Sas

Helmut Straubinger

Johannes Jung

Arnulf Mayer

Michael J Girard

Randy Matthew Lane

Christoph Damm

Markus Ferrari

Thomas Peschel

Volker Guyenot

Hans Reiner Figulla

Nadine Stappenbeck

Thomas Töllner

Michael Litzenburger

Amir Miller

Georg Rahmig

Coralie Marchand

Jonannes Jung

This disclosure relates to a catheter system for introducing a heart valve stent into the body of a patient. The catheter system includes a catheter tip having a seat portion for accommodating the stent in its collapsed state and a stent holder for releasably fixing the stent, wherein the seat portion is constituted by a first sleeve and a second sleeve, said sleeves being moveable relative to each other and relative to the stent holder, and a catheter shaft for connecting the catheter tip to a handle.

Catheter system for introducing an expandable stent into the body of a patient

Disclosed is an improved stent and a related replacement heart valve prosthesis exhibiting various features for improved fixation and crush resistance. The stent is characterized by an inner stent fixed to an outer stent with connecting struts. The stent and heart valve prosthesis can be used for replacement of a defective endogenous heart valve.

Stent and replacement heart valve prosthesis with improved fixation features

The present invention relates to a stent () for the positioning and anchoring of a valvular prosthesis () in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis () fastened to a stent () will occur relative the stent () in the implanted state of the stent (), even given the peristaltic motion of the heart, the stent () according to the invention comprises at least one fastening portion () via which the valvular prosthesis () is connectable to the stent (). The stent () further comprises positioning arches () and retaining arches (), whereby at least one positioning arch () is connected to at least one retaining arch () via a first connecting land (). The stent () moreover comprises at least one auxiliary retaining arch () which connects the respective arms () of the at least one retaining arch () connected to the at least one positioning arch ().

Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient

The present invention relates to a heart valve prosthesis loading device and a method for loading a heart valve prosthesis onto a delivery system.

Loading tool and method for loading a prosthesis

The present invention relates to a double steerable sheath, a delivery system comprising such a sheath and a method for deployment of a medical device, e.g. a replacement heart valve prosthesis, in a patient's heart.

Double steerable sheath and method for deployment of a medical device

The present invention relates to a stent () for the positioning and anchoring of a valvular prosthesis () in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis () fastened to a stent () will occur relative the stent () in the implanted state of the stent (), even given the peristaltic motion of the heart, the stent () according to the invention comprises at least one fastening portion () via which the valvular prosthesis () is connectable to the stent (). The stent () further comprises positioning arches () and retaining arches (), whereby at least one positioning arch () is connected to at least one retaining arch () via a first connecting land (). The stent () moreover comprises at least one auxiliary retaining arch () which connects the respective arms (&#x2033;) of the at least one retaining arch () connected to the at least one positioning arch ().

The invention relates to catheter system for introducing an expandable heart valve stent () into the body of a patient, the catheter system comprising: a catheter tip () having a seat portion for accommodating the stent () in its collapsed state and a stent holder () for releasably fixing the stent (), wherein the seat portion is constituted by a first sleeve-shaped member () and a second sleeve-shaped member (), said sleeve-shaped members () being moveable relative to each other and relative to the stent holder (), and a catheter shaft () for connecting the catheter tip () to a handle (). The catheter shaft () comprising: first force transmitting means () connected to the first sleeve-shaped member (), second force transmitting means () connected to the second sleeve-shaped member () and a distal end section connectable to second operating means () of the handle (), and guiding means () having a passageway extending there between, wherein the first and second force transmitting means () are at least partly received within the passageway such as to be moveable relative to the guiding means (), and wherein the proximal end of the guiding means () terminates distal to the catheter tip ().

Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect

A method of placing an implant including a stent at a native heart valve site includes orienting an expandable body of the stent such that a first open end of the stent is upstream a second open end of the stent relative to a direction of blood flow through a native heart valve. The native heart valve includes native leaflets and an annulus. The method also includes radially expanding a plurality of positioning arches positioned around an outer perimeter of the expandable body. The method additionally includes inserting the plurality of positioning arches respectively within a plurality of pockets defined by leaflets of the native heart valve and a heart structure from which the native leaflets extend. The method further includes radially expanding the first open end of the stent into a position upstream of the annulus and out of contact with nerve bundles.

Catheter system

A device configured for implantation at a heart valve comprises an expandable stent. The stent comprises a first stent segment extending along a first length portion of the stent. The first stent segment is configured to be positioned and radially expanded against a vascular wall of a native aortic valve site. The first stent segment comprises a plurality of closed cell structures defining a circumference of the stent along the first length portion. The plurality of closed cell structures has a uniform density around the circumference. The stent also comprises a second stent segment disposed along a second length portion of the stent. The second stent segment comprises a plurality of interconnected strut members disposed around a circumference of the stent in alternating regions having a first strut density and a second strut density. The first strut density is higher than the second strut density.

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Aschheim, Germany

Helmut Straubinger