Csem Centre Suisse D'electronique Et De Microtechnique Sa&#x2014;recherche Et D&#xe9;veloppement

Hamilton Bonaduz Ag

Csem Centre Suisse D'electronique Et De Microtechnique Sa - Recherche Et Developpment

Tecan Trading Ag

Csem Centre Suisse D'electronique Et De Microtechnique Sa

Tecan Schweiz Ag

Helmut Knapp

Noa Schmid

Siegfried Graf

Janko Auerswald

Vinzenz Kirste

Christian Beyer

Tobias Seiler

Anne-Claire Pliska

Vincent Revol

Urs Lendenmann

Matthias Höchemer

Fabian Winter

Jonas Goldowsky

Thomas Stöckli

Philipp Schmid

Christian Andreas Bosshard

Mark Fretz

Disclosed is a method of measuring a volume of a liquid provided in at least one receptacle, including the steps of: providing a receptacle having at least one cavity for holding a liquid; providing a plenoptic camera positioned so as to be able to image the surface of the liquid; positioning the receptacle such that the liquid surface faces an objective lens of the plenoptic camera; making at least one plenoptic image of the surface of the liquid by way of the plenoptic camera; determining a surface topography of the liquid on the basis of the at least one image; calculating the volume of liquid based on the measured surface topography and at least one known dimension and/or position of the cavity.

Liquid level detection in receptacles using a plenoptic camera to measure the surface topography of the liquid

A method dispenses and/or aspirates a predetermined volume of fluid from a chamber. The chamber includes a lower portion containing fluid and an upper portion containing gas. The method includes measuring an initial pressure in the upper portion and introducing or evacuating a known quantity of gas into or out of the upper portion. The volume of gas in the upper portion is determined based on the volume of gas introduced or evacuated from the upper portion and a measured change in pressure in the upper portion. An upper portion target pressure that will dispense or aspirate a predetermined volume of fluid is determined. A controllable valve is opened while the pressure in the upper portion of the chamber is monitored. Once the target pressure is reached, the predetermined volume of fluid has been dispensed or aspirated, and the controllable valve is then closed.

Apparatus and method for dispensing or aspirating fluid

The present invention discloses a sample sorter system adapted to receive and sort samples according to predetermined criteria. The sample sorter system comprises a receptacle that is adapted to receive and retain fluid and samples. The receptacle is operatively coupled with a drive and with a power source such that actuation of the drive causes the rotation of at least one circular component, which in turn causes the development of a flow regime in the receptacle such that the samples suspended in the fluid are conveyable along a closed path to at least one sample handling site that are positioned along said closed path.

Device, system and method for storing and sorting cellular samples

The present invention discloses a microinjection apparatus () for microinjection of substances into individual substances comprising at least one carrier () on which at least one sample is immobilizable. In embodiments, the apparatus comprises at drivable support () on which at least one carrier is positioned, wherein the support drives the at least one carrier in a closed loop to a respective plurality of stations along the loop. The plurality of stations constitutes at least one sample-substance-providing station (), at least one sample-substance microinjection station () and at least one sample-extraction station ().

Microinjection apparatus and method

A pipette device including a metering liquid receptacle designed to be filled, at least in part, with working fluid and which has a pipette opening as a first tapering of cross-section of flow, a pressure change device which is designed to change the pressure of the working fluid in the metering liquid receptacle, and a throttle point in a pipette duct designed to be filled with working fluid as a further tapering of cross-section of flow. The throttle point is arranged fluid-mechanically between the metering liquid receptacle and the pressure change device and is dimensioned in such a way that a ratio of a flow resistance of the pipette opening for dispensed metering liquid to a flow resistance of the throttle point for working fluid, which flows through the throttle point when the metering fluid is dispensed, is less than 0.5.

Pipette device having a throttle point in the pipette duct

The present invention relates to a device () for calibrating a pipette or a dispensing system comprising a plate (), said plate () comprising at least one channel () with a loading port () for receiving a test volume of a fluid at one end of the at least one channel and an opening () at the other end of the at least one channel, wherein the at least one channel () is constructed as a capillary. Furthermore, the invention relates to a method for calibrating a pipette or a dispensing system, comprising the steps of introducing a first volume of a fluid into a loading port () of a device (), recording a first length of the fluid column in a channel () of the device (), introducing a second volume of a fluid from the pipette or the dispensing system to be calibrated to the same loading port (), recording a second length of the fluid column in the channel (), and computing the volume dispensed by the pipette or the dispensing system by calculating the distance between the second length and the first length and multiplying said distance with the cross-section of the channel ().

Device and method for calibrating a pipette or a dispensing system

The present invention discloses a pressure measurement device comprising: a substrate that includes at least one pressure sensing module and at least one fluid-conductive channel, wherein each channel has a first aperture and a second aperture. The substrate is flexible such that the pressure measurement device is conformably adjustable onto an object's surface. The first aperture is located on the substrate such that when the substrate is suitably adjusted onto the object's surface, the first aperture is open to the exterior of the object's surface. The pressure sensors module is operatively connected to at least one of the second apertures, such that the at least one pressure sensing module is generally being subjected to the pressure being present at the first aperture.

Pressure measurement device and system, and method for manufacturing and using the same

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Ebikon, Switzerland

Helmut Knapp