Basf Aktiengesellschaft

Knoll Aktiengesellschaft

Helmut Fricke

Joerg Rosenberg

Jorg Breitenbach

Werner Maier

Karl Kolter

Werner Bertleff

Thomas Moest

Hans-Peter Harz

Reiner Witt

Ulrich Br&ouml;ckel

Volker Buehler

Ernst Flaig

Herbert Mueller-Peltzer

A process for producing agglomerates with a core/shell structure, in which i) initial agglomerates containing a first particulate solid are prepared; ii) a second particulate solid is agglomerated in the presence of the initial agglomerates with the addition of a binder liquid to give second stage agglomerates and, where appropriate, iii) an nth (n&gE;3) solid is agglomerated in the presence of the (n&minus;1)th stage agglomerates with the addition of a binder liquid to give nth stage agglomerates.

Method for producing agglomerates comprising a core-shell structure

Process and apparatus for the production of divisible tablets

Delayed release microtablet of .beta.-phenylpropiophenone derivatives

A solid drug form containing not less than 90% by weight verapamil is produced by granulating at from 30.degree. to 55.degree. C. with a little water, drying and, where appropriate, conventional tableting or by pelleting, in which case the granules obtained as described are, after cooling, moistened once again and compacted in a granulating mixer at from 30.degree. to 55.degree. C. and are dried.

Solid drug form with a high verapamil content

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Mutterstadt, Germany

Helmut Fricke