Glykos Finland Oy

Novartis International Pharmaceutical, Ltd.

Heli Viskari

Jari Natunen

Markku Saloheimo

Anne Kanerva

Anne Huuskonen

Merja Elisa Penttila

Merja Penttilä

Juhani Saarinen

Ann Westerholm-Parvinen

Christopher Landowski

Jukka Hiltunen

Anna-Liisa Hänninen

Noora Salovuori

Hanna Salo

Jussi Joensuu

Described herein are compositions including filamentous fungal cells, such asfungal cells, having reduced protease activity and expressing fucosylation pathway. Further described herein are methods for producing a glycoprotein having fucosylated N-glycan, using genetically modified filamentous fungal cells, for example,fungal cells, as the expression system.

Production of fucosylated glycoproteins

The present disclosure relates to recombinant proteins having N-acetylglucosaminyltransferase activity. The present disclosure further relates to methods for producing complex N-glycans including the steps of providing host cells containing such recombinant proteins and culturing the host cells such that the recombinant proteins are expressed.

Fusion enzymes

Growing community of inventors

Nummela, Finland

Heli Viskari