Philip Morris Products S.a.

Helene Laparra

Lucien Bovet

Shunhong Dai

Prisca Campanoni

Simon Goepfert

Karen Oishi

Sandrine Roesti

Rosa Cabrera

Julien Beuchat

Gustavo Ramirez

Claudio Facchinetti

Nicolas Lugon-Moulin

Richard Mundell

There is described herein a mutant, non-naturally occurring or transgenic plant or part thereof having reduced expression of the gene encoding Terminal Flower 1 (TFL1) or reduced activity of the protein encoded by TFL1, said TFL1 comprising, consisting or consisting essentially of (i) a polynucleotide sequence comprising, consisting or consisting essentially of a sequence having at least 72% sequence identity to SEQ ID NO:7 or SEQ ID NO:8 or SEQ ID NO:10 or SEQ ID NO:11 or SEQ ID NO:19 or SEQ ID NO:20; or (ii) a polypeptide encoded by the polynucleotide set forth in (i); or (iii) a polypeptide having at least 72% sequence identity to SEQ ID NO:9 or SEQ ID NO:12 or SEQ ID NO:21; wherein the expression or activity of the polynucleotide or the polypeptide set forth in (i), (ii) or (iii) is reduced as compared to a control plant in which the expression or activity of the polynucleotide or the polypeptide set forth in (i), (ii) or (iii) has not been reduced.

Plants with shortened time to flowering

The present invention relates to protein expression in plants, particularly the large-scale production of recombinant polypeptides in wholeplants. The use of preselected combination ofvarieties andstrains, optionally including one or more improvements to the transient expression-based methods of the invention, enables the production of large quantities of a heterologous polypeptides economically and in a short period of time.

Protein expression in plants

Growing community of inventors

Neuchatel, Switzerland

Helene Laparra