Novo Nordisk A/s

Helene Juhldal Knopper

Carsten Lund

Niels Frederik Keiser-Nielsen

The present application relates to methods and devices for providing a reduced risk of free flow from medical devices such as an infusion pump. A medicament containing reservoir () is provided with a piston having a sealing portion () formed by a material of a first stiffness. The piston further comprises a core member () of a material having a stiffness larger than said first stiffness, the core member comprising one or more connective members () being adapted to cooperate with said one or more protrusions of the linear actuation member. The one or more connective members being adapted to be substantially rigid in the axial direction while being resilient in a radial direction, thereby forming a releasable snap or friction fit connection with the linear actuation member. Thereby a mechanism is provided which is engageable by a purely axial relative displacement and which is disengageable by retracting the linear actuation member axially relative to the piston by exerting a pulling force greater than a predetermined limit.

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Frederiksberg, Denmark

Helene Juhldal Knopper