Bacterin International, Inc.

Bacterin Interational, Inc.

Helena M Lovick

Todd Meyer

Daniel Cox

Gregory Juda

Michael Mansfield

Mark Schallenberger

Dominic Denty

The present invention relates to compressed bone-based products and methods to make the same. The maintained compressed state of the product serves to enhance the product's inherent osteoconductivity.

Expandable bone grafts and methods of manufacture thereof

Methods of making articles with a 3D printer using biomaterials that retain physical properties and biological activity are discussed. Methods can include providing a crosslinkable material and a biomaterial to a 3D printer, and crosslinking the materials to form an implant. Biomaterials can include, among other things, bone, or tissue.

Methods of manufacturing crosslinkable 3D printed biomaterial-based implants

A hydration media for biological tissue products, methods of making the same and methods of using the same is provided. The hydration media includes sodium phosphate and calcium silicate and can be used to store or hydrate a biological tissue product.

Hydration media for biological tissue products, methods of making the same and methods of using

The present invention relates to shaped, bone fiber-based products and methods to make the same.

Shaped bone fiber-based products and a method of manufacture thereof

A bone graft substitute for use in orthopedic bone grafting procedures comprising a radiolucent bone graft substitute combined with a temporary radiopaque agent. Methods of making and using the composition are also disclosed. Bone graft substitutes have become an effective means of regenerating bone in orthopedic procedures where bone loss results from surgically created defects or traumatic injury to the bone. Bone graft substitutes include mineral-based materials such as hydroxyapatite, calcium phosphates, and calcium phosphosilicates as well as allograft-derived materials and xenograft-derived materials such as collagen-based matrices and demineralized bone matrices.

Bone graft substitute containing a temporary contrast agent and a method of generating such and a method of use thereof

The invention provides articles of 3D printed biomaterials with retained physical properties and biological activity and methods of using the articles. Furthermore, the invention provides manufacturing conditions to generate 3D printed biomaterials with highly preserved biological activity.

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N. Great Falls, MT, United States of America

Helena M Lovick